双岐四联活菌片联合蒙脱石散治疗小儿腹泻临床疗效观察(1)
摘要：目的 探讨双岐四联活菌片联合蒙脱石散治疗小儿腹泻临床疗效。方法 选取2017年1月～2018年1月我院收治的小儿腹泻患儿100例，随机分为观察组和对照组，每组50例。对照组采用蒙脱石散治疗，观察组在对照组基础上加用双岐四联活菌片治疗。比较两组患者的临床疗效、用药前后腹泻积分、小儿营养情况(ALB、HGB、TP)、止瀉的平均天数、腹痛持续时间、体温正常时间、呕吐消失时间以及不良反应情况。结果 观察组总有效率为98.00%，高于对照组的78.00%，差异具有统计学意义(P<0.05)。用药后观察组腹泻积分为(0.25±0.05)分，低于对照组的(1.14±0.11)分，差异具有统计学意义(P<0.05);观察组ALB、HGB、TP水平均高于对照组，差异具有统计学意义(P<0.05)。观察组止泻平均天数、腹痛持续时间、体温正常时间、呕吐消失时间均短于对照组，差异具有统计学意义(P<0.05)。两组不良反应发生率比较，差异无统计学意义(P>0.05)。结论 蒙脱石散联合双岐四联活菌片治疗小儿腹泻，临床疗效显著，可加速病情康复，改善营养情况，安全性好。
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关键词：双岐四联活菌片;蒙脱石散;小儿腹泻
中图分类号：R725.7 文献标识码：A DOI：10.3969/j.issn.1006-1959.2019.06.051
文章编号：1006-1959(2019)06-0159-03
Abstract：Objective To investigate the clinical efficacy of Bifidobacterium tetracycline tablet combined with Montmorillonite powder in the treatment of diarrhea in children. Methods A total of 100 children with diarrhea in our hospital from January 2017 to January 2018 were randomly divided into observation group and control group， with 50 cases in each group. The control group was treated with Montmorillonite powder， and the observation group was treated with the Bifidobacterium tetracycline tablet on the basis of the control group. The clinical efficacy， diarrhea score before and after medication， pediatric nutrition (ALB， HGB， TP)， average days of diarrhea， duration of abdominal pain， normal temperature of body temperature， time of disappearance of vomiting， and adverse reactions were compared between the two groups. Results The total effective rate of the observation group was 98.00%， which was higher than that of the control group 78.00%，the difference was statistically significant (P<0.05). After treatment， the score of diarrhea in the observation group was (0.25±0.05)， which was lower than that in the control group (1.14±0.11)，the difference was statistically significant (P<0.05). The ALB， HGB and TP levels in the observation group were higher than those in the control group，the difference was statistically significant (P<0.05). The average days of diarrhea， duration of abdominal pain， normal temperature of body temperature， and disappearance of vomiting were shorter in the observation group than in the control group，the difference was statistically significant (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion The combination of Montmorillonite powder and Bifidobacterium tetracycline tablet in the treatment of diarrhea in children has a significant clinical effect， which can accelerate the recovery of the disease， improve the nutritional status and safety., 百拇医药(廖道明 朱茜)
, http://www.100md.com
关键词：双岐四联活菌片;蒙脱石散;小儿腹泻
中图分类号：R725.7 文献标识码：A DOI：10.3969/j.issn.1006-1959.2019.06.051
文章编号：1006-1959(2019)06-0159-03
Abstract：Objective To investigate the clinical efficacy of Bifidobacterium tetracycline tablet combined with Montmorillonite powder in the treatment of diarrhea in children. Methods A total of 100 children with diarrhea in our hospital from January 2017 to January 2018 were randomly divided into observation group and control group， with 50 cases in each group. The control group was treated with Montmorillonite powder， and the observation group was treated with the Bifidobacterium tetracycline tablet on the basis of the control group. The clinical efficacy， diarrhea score before and after medication， pediatric nutrition (ALB， HGB， TP)， average days of diarrhea， duration of abdominal pain， normal temperature of body temperature， time of disappearance of vomiting， and adverse reactions were compared between the two groups. Results The total effective rate of the observation group was 98.00%， which was higher than that of the control group 78.00%，the difference was statistically significant (P<0.05). After treatment， the score of diarrhea in the observation group was (0.25±0.05)， which was lower than that in the control group (1.14±0.11)，the difference was statistically significant (P<0.05). The ALB， HGB and TP levels in the observation group were higher than those in the control group，the difference was statistically significant (P<0.05). The average days of diarrhea， duration of abdominal pain， normal temperature of body temperature， and disappearance of vomiting were shorter in the observation group than in the control group，the difference was statistically significant (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion The combination of Montmorillonite powder and Bifidobacterium tetracycline tablet in the treatment of diarrhea in children has a significant clinical effect， which can accelerate the recovery of the disease， improve the nutritional status and safety., 百拇医药(廖道明 朱茜)