四川省肿瘤医院2005~2018年肿瘤住院患者HIV抗体筛查结果分析(1)
摘要：目的 了解四川省肿瘤医院2005～2018年肿瘤住院患者HIV的感染状况和流行特征。方法 采用酶联免疫吸附(ELISA)法对我院237472例住院患者进行HIV抗体检测，同时对HIV抗体阳性患者的临床资料进行回顾性分析。结果 住院肿瘤患者HIV抗体的总体阳性率为1.42‰(338/237472)，其中男性患者HIV抗体阳性检出率为2.18‰(244/111885)，女性患者HIV抗体阳性检出率为0.75‰(94/125587)，性别差异有统计学意义(P<0.05);年龄组以21～30岁检出率最高2.18‰;病种以头颈病区的头颈部肿瘤所占构成比最大21.89%;职业分布较广，且以农村居民为主(48.57%)。结论 住院肿瘤患者HIV感染例数呈逐年上升趋势，以中老年男性为主，并存在病区、病种、职业构成差异的特点，为确保医患安全和防止院内感染，应对住院肿瘤患者HIV进行长期监测。
关键词：人类免疫缺陷病毒;肿瘤患者;HIV抗体
中图分类号：R512.91 文献标识码：A DOI：10.3969/j.issn.1006-1959.2019.07.024
, http://www.100md.com
文章编号：1006-1959(2019)07-0082-04
Abstract：Objective To understand the HIV status and epidemiological characteristics of tumor inpatients in the Sichuan Cancer Hospital from 2005 to 2018. Methods ELISA analysis was performed on 237，472 inpatients in our hospital by enzyme-linked immunosorbent assay (ELISA). The clinical data of HIV-positive patients were retrospectively analyzed. Results The overall positive rate of HIV antibody in hospitalized patients was 1.42‰ (338/237472). The positive rate of HIV antibody in male patients was 2.18‰ (244/111885)， and the positive rate of HIV antibody in female patients was 0.75‰ (94/125587)， the gender difference was statistically significant (P<0.05); the age group had the highest detection rate of 2.18‰ from 21 to 30 years old; the head and neck tumors in the head and neck area accounted for the largest ratio of 21.89%; occupation It is widely distributed and is dominated by rural residents (48.57%). Conclusion In order to ensure the safety of doctors and patients and to prevent nosocomial infection， the number of cases of HIV infection in inpatients with tumor showed an increasing trend year by year， mainly in middle-aged and elderly men， and there were differences in disease area， disease type and occupation composition. Long-term monitoring of HIV should be performed in inpatients with tumor.
, 百拇医药
Key words：Human immunodeficiency virus;Tumor patient;HIV antibody
獲得性免疫缺陷综合征(AIDS)亦称艾滋病，是由人类免疫缺陷病毒(HIV)感染而引起的以免疫系统损害和感染为主要特征的一种危害严重的病毒性传染疾病，已成为世界性的社会问题和公共卫生问题[1-4]。为了解HIV在住院肿瘤患者中的感染状况和流行特征，进而给临床应对HIV感染提供科学依据，本文对2005～2018年近14年的20余万份样本进行HIV抗体检测，并将HIV抗体初筛阳性者血清送至四川省疾病预防控制中心复检验证，并对阳性患者的临床资料进行回顾性统计分析，现报道如下。
1资料与方法
1.1资料来源 研究对象为2005年1月1日～2018年12月31日四川省肿瘤医院237472例肿瘤初诊患者，其中男性患者111885例，女性患者125587例，年龄1个月～106岁，中位年龄57岁。收集所有患者的临床病历资料，包括住院年份、年龄、性别、入院科室、诊断、婚姻状况、职业、文化程度等。, 百拇医药(曹鸣菲 雷德财 宋晓玉)
关键词：人类免疫缺陷病毒;肿瘤患者;HIV抗体
中图分类号：R512.91 文献标识码：A DOI：10.3969/j.issn.1006-1959.2019.07.024
, http://www.100md.com
文章编号：1006-1959(2019)07-0082-04
Abstract：Objective To understand the HIV status and epidemiological characteristics of tumor inpatients in the Sichuan Cancer Hospital from 2005 to 2018. Methods ELISA analysis was performed on 237，472 inpatients in our hospital by enzyme-linked immunosorbent assay (ELISA). The clinical data of HIV-positive patients were retrospectively analyzed. Results The overall positive rate of HIV antibody in hospitalized patients was 1.42‰ (338/237472). The positive rate of HIV antibody in male patients was 2.18‰ (244/111885)， and the positive rate of HIV antibody in female patients was 0.75‰ (94/125587)， the gender difference was statistically significant (P<0.05); the age group had the highest detection rate of 2.18‰ from 21 to 30 years old; the head and neck tumors in the head and neck area accounted for the largest ratio of 21.89%; occupation It is widely distributed and is dominated by rural residents (48.57%). Conclusion In order to ensure the safety of doctors and patients and to prevent nosocomial infection， the number of cases of HIV infection in inpatients with tumor showed an increasing trend year by year， mainly in middle-aged and elderly men， and there were differences in disease area， disease type and occupation composition. Long-term monitoring of HIV should be performed in inpatients with tumor.
, 百拇医药
Key words：Human immunodeficiency virus;Tumor patient;HIV antibody
獲得性免疫缺陷综合征(AIDS)亦称艾滋病，是由人类免疫缺陷病毒(HIV)感染而引起的以免疫系统损害和感染为主要特征的一种危害严重的病毒性传染疾病，已成为世界性的社会问题和公共卫生问题[1-4]。为了解HIV在住院肿瘤患者中的感染状况和流行特征，进而给临床应对HIV感染提供科学依据，本文对2005～2018年近14年的20余万份样本进行HIV抗体检测，并将HIV抗体初筛阳性者血清送至四川省疾病预防控制中心复检验证，并对阳性患者的临床资料进行回顾性统计分析，现报道如下。
1资料与方法
1.1资料来源 研究对象为2005年1月1日～2018年12月31日四川省肿瘤医院237472例肿瘤初诊患者，其中男性患者111885例，女性患者125587例，年龄1个月～106岁，中位年龄57岁。收集所有患者的临床病历资料，包括住院年份、年龄、性别、入院科室、诊断、婚姻状况、职业、文化程度等。, 百拇医药(曹鸣菲 雷德财 宋晓玉)