高频通气在单肺通气低氧血症的临床应用(1)
摘要:目的 探究高频通气在单肺通气低氧血症的临床应用及其效果。方法 选取我院2016年4月~2018年3月收治的62例行胸外科手术的患者作为研究对象,随机分为对照组和观察组,每组31例。对照组采用单肺通气,观察组采用高频通气,比较两组的治疗前后的血气分析指标和各时间点血流动力学指标。结果 治疗后,观察组PaO2、PaCO2均优于对照组,差异有统计学意义(P<0.05),两组治疗前后pH值比较,差异无统计学意义(P>0.05)。在10 min、20 min等时间点的HR、MAP的比较中,两组均无统计学意义(P>0.05)。结论 高频通气应用在单肺通气低氧血症中,可以有效改善血气指标,对血流动力学产生的影响较小,从而有效改善低氧血症现象。
关键词:高频通气;单肺通气;低氧血症
中图分类号:R614 文献标识码:A DOI:10.3969/j.issn.1006-1959.2019.10.039
, 百拇医药
文章编号:1006-1959(2019)10-0119-03
Abstract:Objective To investigate the clinical application and effect of high-frequency ventilation in single-lung ventilation hypoxemia.Methods A total of 62 patients undergoing thoracic surgery from April 2016 to March 2018 were enrolled in the study. They were randomly divided into control group and observation group, with 31 cases in each group. The control group was treated with single-lung ventilation, and the observation group was treated with high-frequency ventilation. The blood gas analysis indexes and hemodynamic indexes at each time point were compared between the two groups.Results After treatment, PaO2 and PaCO2 in the observation group were better than the control group, the difference was statistically significant (P<0.05). There was no significant difference in pH value between the two groups before and after treatment(P>0.05).There was no significant difference between the two groups in the comparison of HR and MAP at 10 min and 20 min(P>0.05).Conclusion High-frequency ventilation in single-lung ventilation hypoxemia can effectively improve blood gas parameters and have less effect on hemodynamics, thus effectively improving hypoxemia.
, 百拇医药
Key words:High frequency ventilation;Single lung ventilation;Hypoxemia
胸腔外科手术中,单肺通气对术侧肺的隔离效果比较理想,能够拓宽手术的视野,提升手术期间视野的清晰度,因而其应用比较的普遍,具有较高的使用率[1-3]。但是从临床大量的研究实践来看,单肺通气的应用会导致肺内分流出现增加,引发一定的低氧血症,影响治疗的效果[4,5]。要想进一步提升单肺通气应用的效果,提高手术的治疗水平,必须要采取相应的措施防止低氧血症的发生。研究表明,高频通气应用在单肺通气引发的低氧血症中,能够有效改善该症状,满足肺保护性通气策略的目标[6]。本研究为进一步了解高频通气在单肺通气低氧血症中的应用效果,将我院胸外科在2016年4月~2018年3月收治的62例手术患者做为研究对象进行研究,现报道如下。
1资料与方法
1.1一般资料 选取2016年4月~2018年3月在曲靖市第一人民医院胸外科接受治疗的手术患者62例作为研究对象,采用随机数字表法分为对照组和观察组,每组31例。本研究经医院伦理委员会批准,患者均知情同意,并签署知情同意书。纳入标准:①术前无明显血流动力学障碍;②术前无明显肺功能障碍;③心、肝、肾功能正常。排除标准:①可疑或存在困难气道患者;②术前使用镇痛、镇静药物;③合并严重的心、肝、肾等器质性损伤者;④依从性不高者;⑤基本资料不全者。对照组男21例,女10例;年龄43~78歲,平均年龄(58.91±2.34)岁;肺叶楔形切除12例、食管癌10例、胸膜活检术7例、其它2例。观察组男22例,女9例;年龄42~76岁,平均年龄(58.03±2.45)岁;肺叶楔形切除13例、食管癌11例、胸膜活检术6例、其它1例。两组一般资料比较,差异无统计学意义(P>0.05),具有可比性。, http://www.100md.com(陈壁 李剑钢 沈国灿 桂琳)
关键词:高频通气;单肺通气;低氧血症
中图分类号:R614 文献标识码:A DOI:10.3969/j.issn.1006-1959.2019.10.039
, 百拇医药
文章编号:1006-1959(2019)10-0119-03
Abstract:Objective To investigate the clinical application and effect of high-frequency ventilation in single-lung ventilation hypoxemia.Methods A total of 62 patients undergoing thoracic surgery from April 2016 to March 2018 were enrolled in the study. They were randomly divided into control group and observation group, with 31 cases in each group. The control group was treated with single-lung ventilation, and the observation group was treated with high-frequency ventilation. The blood gas analysis indexes and hemodynamic indexes at each time point were compared between the two groups.Results After treatment, PaO2 and PaCO2 in the observation group were better than the control group, the difference was statistically significant (P<0.05). There was no significant difference in pH value between the two groups before and after treatment(P>0.05).There was no significant difference between the two groups in the comparison of HR and MAP at 10 min and 20 min(P>0.05).Conclusion High-frequency ventilation in single-lung ventilation hypoxemia can effectively improve blood gas parameters and have less effect on hemodynamics, thus effectively improving hypoxemia.
, 百拇医药
Key words:High frequency ventilation;Single lung ventilation;Hypoxemia
胸腔外科手术中,单肺通气对术侧肺的隔离效果比较理想,能够拓宽手术的视野,提升手术期间视野的清晰度,因而其应用比较的普遍,具有较高的使用率[1-3]。但是从临床大量的研究实践来看,单肺通气的应用会导致肺内分流出现增加,引发一定的低氧血症,影响治疗的效果[4,5]。要想进一步提升单肺通气应用的效果,提高手术的治疗水平,必须要采取相应的措施防止低氧血症的发生。研究表明,高频通气应用在单肺通气引发的低氧血症中,能够有效改善该症状,满足肺保护性通气策略的目标[6]。本研究为进一步了解高频通气在单肺通气低氧血症中的应用效果,将我院胸外科在2016年4月~2018年3月收治的62例手术患者做为研究对象进行研究,现报道如下。
1资料与方法
1.1一般资料 选取2016年4月~2018年3月在曲靖市第一人民医院胸外科接受治疗的手术患者62例作为研究对象,采用随机数字表法分为对照组和观察组,每组31例。本研究经医院伦理委员会批准,患者均知情同意,并签署知情同意书。纳入标准:①术前无明显血流动力学障碍;②术前无明显肺功能障碍;③心、肝、肾功能正常。排除标准:①可疑或存在困难气道患者;②术前使用镇痛、镇静药物;③合并严重的心、肝、肾等器质性损伤者;④依从性不高者;⑤基本资料不全者。对照组男21例,女10例;年龄43~78歲,平均年龄(58.91±2.34)岁;肺叶楔形切除12例、食管癌10例、胸膜活检术7例、其它2例。观察组男22例,女9例;年龄42~76岁,平均年龄(58.03±2.45)岁;肺叶楔形切除13例、食管癌11例、胸膜活检术6例、其它1例。两组一般资料比较,差异无统计学意义(P>0.05),具有可比性。, http://www.100md.com(陈壁 李剑钢 沈国灿 桂琳)