甲状腺切除术治疗分化型甲状腺癌的疗效(1)
摘要：目的 探討甲状腺切除术治疗分化型甲状腺癌的临床疗效及安全性。方法 选取2018年2月～11月我院收治的分化型甲状腺癌患者80例，根据手术方法分为两组，其中40例采取甲状腺全切除术作为全切组，另外40例采取甲状腺次全切除术作为次全切组，比较两组临床疗效、手术时间、术中出血量、住院时间、促甲状腺激素(TSH)、甲状腺球蛋白(Tg)、抗甲状腺球蛋白抗体(TgAb)及并发症发生情况。结果 全切组总有效率为95.00%，高于次全切组的72.50%，差异有统计学意义(P<0.05);全切组手术时间、术中出血量均低于次全切组，差异有统计学意义(P<0.05);全切组患者TSH、Tg、TgAb水平均低于次全切组，差异有统计学意义(P<0.05);全切组并发症发生率(52.50%)高于次全切组(27.50%)，差异有统计学意义(P<0.05)。结论 甲状腺全切除术治疗分化型甲状腺癌疗效较好，手术时间和术中出血量少，有助于改善患者甲状腺指标，但并发症相对较多。
关键词：甲状腺切除术;甲状腺次全切除术;分化型甲状腺癌
中图分类号：R736.1 文献标识码：A DOI：10.3969/j.issn.1006-1959.2019.12.034
文章编号：1006-1959(2019)12-0109-03
Abstract：Objective To investigate the clinical efficacy and safety of thyroidectomy for differentiated thyroid cancer. Methods 80 patients with differentiated thyroid cancer admitted to our hospital from February to November 2018 were enrolled. According to the surgical method， 40 patients were divided into two groups. 40 patients underwent total thyroidectomy and 40 patients underwent subtotal thyroidectomy. As a sub-total cut group， the clinical efficacy， operation time， intraoperative blood loss， hospital stay， thyroid stimulating hormone (TSH)， thyroglobulin (Tg)， anti-thyroglobulin antibody (TgAb) and complications were compared between the two groups.Results The total effective rate of the total cut group was 95.00%， which was higher than that of the subtotal cut group 72.50%，the difference was statistically significant (P<0.05). The total operation time and intraoperative blood loss were lower than the subtotal cut group，the difference was statistically significant (P<0.05). The TSH， Tg， and TgAb levels in the total cut group were lower than those in the subtotal cut group， the difference was statistically significant (P<0.05); The incidence of complications in the total cut group (52.50%) was higher than that in the subtotal cut group (27.50%)，the difference was statistically significant (P<0.05).Conclusion Total thyroidectomy is effective in the treatment of differentiated thyroid cancer. The operation time and intraoperative blood loss are small， which can improve the thyroid index of patients， but the complications are relatively more.
Key words：Thyroidectomy;Subtotal thyroidectomy;Differentiated thyroid cancer, http://www.100md.com(崔艳钊 吴椿泉)
关键词：甲状腺切除术;甲状腺次全切除术;分化型甲状腺癌
中图分类号：R736.1 文献标识码：A DOI：10.3969/j.issn.1006-1959.2019.12.034
文章编号：1006-1959(2019)12-0109-03
Abstract：Objective To investigate the clinical efficacy and safety of thyroidectomy for differentiated thyroid cancer. Methods 80 patients with differentiated thyroid cancer admitted to our hospital from February to November 2018 were enrolled. According to the surgical method， 40 patients were divided into two groups. 40 patients underwent total thyroidectomy and 40 patients underwent subtotal thyroidectomy. As a sub-total cut group， the clinical efficacy， operation time， intraoperative blood loss， hospital stay， thyroid stimulating hormone (TSH)， thyroglobulin (Tg)， anti-thyroglobulin antibody (TgAb) and complications were compared between the two groups.Results The total effective rate of the total cut group was 95.00%， which was higher than that of the subtotal cut group 72.50%，the difference was statistically significant (P<0.05). The total operation time and intraoperative blood loss were lower than the subtotal cut group，the difference was statistically significant (P<0.05). The TSH， Tg， and TgAb levels in the total cut group were lower than those in the subtotal cut group， the difference was statistically significant (P<0.05); The incidence of complications in the total cut group (52.50%) was higher than that in the subtotal cut group (27.50%)，the difference was statistically significant (P<0.05).Conclusion Total thyroidectomy is effective in the treatment of differentiated thyroid cancer. The operation time and intraoperative blood loss are small， which can improve the thyroid index of patients， but the complications are relatively more.
Key words：Thyroidectomy;Subtotal thyroidectomy;Differentiated thyroid cancer, http://www.100md.com(崔艳钊 吴椿泉)