摘要：子痫前期是妊娠期特有的疾病，是一种多系统疾病，其特征在于高血压伴随母体或胎儿一种或多种其他器官系统损害。血小板源性生长因子(PDGF)是一种促有丝分裂剂，涉及细胞的迁徙、增殖、新血管形成及动脉粥样硬化病变的发生、发展。PDGF适度分泌释放对是否发生病理性妊娠极其关键，过度分泌可导致子痫前期胎盘血管病变。现将近年来与子痫前期有关的PDGF的研究进行总结。

    关键词：子痫前期;血小板源性生长因子;动脉粥样硬化病变;不良妊娠结局

    Abstract：Preeclampsia is a disease specific to pregnancy and is a multi-system disease characterized by hypertension accompanied by damage to one or more other organ systems of the mother or fetus. Platelet-derived growth factor (PDGF) is a mitogenic agent involved in cell migration ......