锌剂防治鼻咽癌同步放化疗患者放射性口咽炎的效果分析(4)
[5]Lin LC，Que J，Lin LK，et al.Zinc supplementation to improve mucositis and dermatitis in patients after radiotherapy for head-and-neck cancers：a double-blind，randomized study[J].Int J Radiat Oncol Biol Phys，2006，65(3)：745-750.
[6]Suzuki A，Kobayashi R，Shakui T，et al.Effect of polaprezinc on oral mucositis，irradiation period，and time to discharge in patients with head and neck cancer[J].Head Neck，2016，38(9)：1387-1392.
[7]Doi H，Fujiwara M，Suzuki H，et al.Polaprezinc reduces the severity of radiation-induced mucositis in head and neck cancer patients[J].Mol Clin Oncol，2015，3(2)：381-386.
, http://www.100md.com
[8]Tao Z，Gao J，Qian L，et al.Factors associated with acute oral mucosal reaction induced by radiotherapy in head and neck squamous cell carcinoma：A retrospective single-center experience[J].Medicine(Baltimore)，2017，96(50)：e8446.
[9]Maria OM，Eliopoulos N，Muanza T.Radiation-Induced Oral Mucositis[J].Front Oncol，2017(7)：89.
[10]Livingstone C.Zinc：physiology，deficiency，and parenteral nutrition[J].Nutr Clin Pract，2015，30(3)：371-382.
, 百拇医药
[11]Bao ZX，Yang XW，Shi J，et al.Serum zinc levels in 368 patients with oral mucosal diseases：A preliminary study[J].Med Oral Patol Oral Cir Bucal，2016，21(3)：e335-e340.
[12]Mitsuhashi H，Suemaru K，Li B，et al.Evaluation of topical external medicine for 5-fluorouracil-induced oral mucositis in hamsters[J].Eur J Pharmacol，2006，551(1-3)：152-155.
[13]Hayashi H，Kobayashi R，Suzuki A，et al.Preparation and clinical evaluation of a novel lozenge containing polaprezinc，a zinc-L-carnosine，for prevention of oral mucositis in patients with hematological cancer who received high-dose chemotherapy[J].Med Oncol，2016，33(8)：91.
, 百拇医药
[14]Hayashi H，Kobayashi R，Suzuki A，et al.Polaprezinc prevents oral mucositis in patients treated with high-dose chemotherapy followed by hematopoietic stem cell transplantation[J].Anticancer Res，2014，34(12)：7271-7277.
[15]Lin YS，Lin LC，Lin SW，et al.Discrepancy of the effects of zinc supplementation on the prevention of radiotherapy-induced mucositis between patients with nasopharyngeal carcinoma and those with oral cancers：subgroup analysis of a double-blind，randomized study[J].Nutr Cancer，2010，62(5)：682-691.
, 百拇医药
[16]Sangthawan D，Phungrassami T，Sinkitjarurnchai W.A randomized double-blind，placebo-controlled trial of zinc sulfate supplementation for alleviation of radiation-induced oral mucositis and pharyngitis in head and neck cancer patients[J].J Med Assoc Thai，2013，96(1)：69-76.
[17]Mirabile A，Airoldi M，Ripamonti C，et al.Pain management in head and neck cancer patients undergoing chemo-radiotherapy：Clinical practical recommendations[J].Crit Rev Oncol Hematol，2016(99)：100-106.
收稿日期：2019-5-26;修回日期：2019-6-5
編辑/杨倩, 百拇医药(龚建忠 韦燕 潘琦津)
[6]Suzuki A，Kobayashi R，Shakui T，et al.Effect of polaprezinc on oral mucositis，irradiation period，and time to discharge in patients with head and neck cancer[J].Head Neck，2016，38(9)：1387-1392.
[7]Doi H，Fujiwara M，Suzuki H，et al.Polaprezinc reduces the severity of radiation-induced mucositis in head and neck cancer patients[J].Mol Clin Oncol，2015，3(2)：381-386.
, http://www.100md.com
[8]Tao Z，Gao J，Qian L，et al.Factors associated with acute oral mucosal reaction induced by radiotherapy in head and neck squamous cell carcinoma：A retrospective single-center experience[J].Medicine(Baltimore)，2017，96(50)：e8446.
[9]Maria OM，Eliopoulos N，Muanza T.Radiation-Induced Oral Mucositis[J].Front Oncol，2017(7)：89.
[10]Livingstone C.Zinc：physiology，deficiency，and parenteral nutrition[J].Nutr Clin Pract，2015，30(3)：371-382.
, 百拇医药
[11]Bao ZX，Yang XW，Shi J，et al.Serum zinc levels in 368 patients with oral mucosal diseases：A preliminary study[J].Med Oral Patol Oral Cir Bucal，2016，21(3)：e335-e340.
[12]Mitsuhashi H，Suemaru K，Li B，et al.Evaluation of topical external medicine for 5-fluorouracil-induced oral mucositis in hamsters[J].Eur J Pharmacol，2006，551(1-3)：152-155.
[13]Hayashi H，Kobayashi R，Suzuki A，et al.Preparation and clinical evaluation of a novel lozenge containing polaprezinc，a zinc-L-carnosine，for prevention of oral mucositis in patients with hematological cancer who received high-dose chemotherapy[J].Med Oncol，2016，33(8)：91.
, 百拇医药
[14]Hayashi H，Kobayashi R，Suzuki A，et al.Polaprezinc prevents oral mucositis in patients treated with high-dose chemotherapy followed by hematopoietic stem cell transplantation[J].Anticancer Res，2014，34(12)：7271-7277.
[15]Lin YS，Lin LC，Lin SW，et al.Discrepancy of the effects of zinc supplementation on the prevention of radiotherapy-induced mucositis between patients with nasopharyngeal carcinoma and those with oral cancers：subgroup analysis of a double-blind，randomized study[J].Nutr Cancer，2010，62(5)：682-691.
, 百拇医药
[16]Sangthawan D，Phungrassami T，Sinkitjarurnchai W.A randomized double-blind，placebo-controlled trial of zinc sulfate supplementation for alleviation of radiation-induced oral mucositis and pharyngitis in head and neck cancer patients[J].J Med Assoc Thai，2013，96(1)：69-76.
[17]Mirabile A，Airoldi M，Ripamonti C，et al.Pain management in head and neck cancer patients undergoing chemo-radiotherapy：Clinical practical recommendations[J].Crit Rev Oncol Hematol，2016(99)：100-106.
收稿日期：2019-5-26;修回日期：2019-6-5
編辑/杨倩, 百拇医药(龚建忠 韦燕 潘琦津)