摘要：目的 探讨参麦注射液联合放化疗对中晚期老年食管癌患者效果和毒副反应情况。方法 选取2017年1月～2018年12月临邑县人民医院收治的120例晚期食管癌老年患者为研究对象，将其随机分为对照组和观察组，各60例。对照组采用放射治疗联合卡培他滨治疗，观察组行放射治疗联合参麦注射液治疗，比较两组临床疗效、治疗前后卡氏功能状态评分(KPS评分)和毒副反应发生情况。结果 观察组总有效率(83.33%)高于对照组(76.67%)，差异有统计学意义(P<0.05);治疗后，两组KPS评分均较治疗前升高，且观察组高于对照组，差异有统计学意义(P<0.05);观察组毒副反应总发生率(25.00%)低于对照组(46.67%)，差异有统计学意义(P<0.05)。结论 参麦注射液联合放化疗治疗中晚期食管癌老年患者的临床疗效确切，毒副反应较，能够提高患者生活质量。

    关键词：参麦注射液;放疗;化疗;食管癌

    Abstract：Objective To investigate the effect and side effects of Shenmai injection combined with radiotherapy and chemotherapy on patients with advanced esophageal cancer.Methods A total of 120 elderly patients with advanced esophageal cancer admitted to Linyi County People’s Hospital from January 2017 to December 2018 were selected as the research subjects. They were randomly divided into a control group and an observation group ......