Influence of GSTM1 and GSTT1 Genotypes and Smoking
InfluenceofGSTM1andGSTT1GenotypesandSmoking,AlcoholExposureontheOccurrenceofGastricCan
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Abstract: [Objective] To determine the association between glutathione-s-transferase genetic polymorphisms(GSTM1,GSTF1) and smoking; alcohol exposure with the risk of gastric cancer and elucidate the action and interaction of gene and environmental factors. [ Methods ] 1:1 Case-control study was conducted and polymerase chain reaction technique was employed to analyse the genetic polymorphisms of GST (GSTM1,GSTT1) genotype in 121 cases of patients with gastric cancer and sex, age-matched controls, who were selected from Nanjing Zhongda hospital and Jiangsu Province Cancer Hospital ......
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