超声造影联合补肾活血法治疗输卵管性不孕的临床观察(1)
摘要：目的探讨超声造影联合补肾活血法诊治输卵管性不孕的临床效果。方法将2015年6月—2016年6月于本院诊治的输卵管性不孕患者80例随机分2组，对照组40例用输卵管介入术治疗，观察组40例用过氧化碳酰胺超声下通液+补肾活血大法治疗；详细记录2组患者治疗前后子宫内膜厚度、E2水平变化情况、妊娠情况。结果观察组子宫内膜厚度及E2水平改善程度优于对照组、妊娠情况优于对照组，差异有统计学意义(P<0.05)。结论输卵管性不孕患者选择超声造影+补肾活血法诊治的效果较好，可充分改善患者治疗后子宫内膜厚度及E2水平，可获得较高的妊娠率，值得临床上广泛应用。
关键词：超声造影；补肾活血；输卵管性不孕
中图分类号：R271.14文献标志码：B文章编号：1007-2349(2017)12-0023-03
【Abstract】Objective： To study the clinical effect of contrast-enhanced ultrasound combined with kidney-tonifying and blood activating method on diagnosis and treatment of tubal infertility. Methods： 80 patients who were diagnosed and treated in our hospital from June 2015 to June 2016 were randomly divided into two groups， 40 cases per group. The patients in the control group were treated with tubal intervention while the patients in the observation group were treated with carbamide peroxide ultrasonic fluid plus kidney-tonifying and blood activating method. The endometrial thickness， E2 level changes and pregnancy of the two groups before and after treatment were recorded in detail. Results： The improvement of endometrial thickness and E2 level in observation group was better than that in control group and the pregnancy was better than that of the control group. The difference was statistically significant (P<0.05). Conclusion： The diagnosis and treatment of tubal infertility patients by contrast-enhanced ultrasound and kidney-invigorating and blood-activating method are good， which can fully improve the thickness of endometrium and the level of E2 after treatment， and obtain higher pregnancy rate， worthy of wide application in clinic.
【Key words】contrast-enhanced ultrasound， kidney-invigorating and blood-activating method， tubal infertility
輸卵管因素导致的不孕约占整个不孕症人群45%～55%，是引起女性不孕的首要原因[1]。急慢性盆腔炎等则是导致输卵管性不孕的常见原因，可引起输卵管阻塞、蠕动能力减弱而致不孕。输卵管性不孕是一种相对不孕，且大多为继发性不孕，通过治疗可以获得妊娠。针对输卵管性不孕的治疗，常根据输卵管阻塞部位和程度的不同采用输卵管通液、宫腔镜下输卵管插管通液、宫腹腔镜手术以及辅助生育技术等。社会不断进步，输卵管炎性不孕的临床发病率却逐年上升。在我国经济迅速发展、计划生育不断调整的今天，生育成为了大多数家庭关注的重点。面对输卵管炎性不孕的高发病率，面对输卵管性不孕，如何选择一种简便、易行、疗效可靠的诊治方法，至关重要。本文旨右探讨过氧化碳酰胺超声下通液加补肾活血大法诊治输卵管性不孕的疗效。现将结果报道如下。
1资料与方法
1.1一般资料将2015年6月—2016年6月于本院诊治的输卵管性不孕患者80例随机分为对照组与观察组。对照组40例患者中：年龄24～38岁，平均年龄为(28.16±3.42)岁；病程2～3.5 a，平均病程为(3.14±0.31)a；原发性17例、继发性23例。观察组40例患者中：年龄23～35岁，平均年龄为(27.01±3.17)岁；病程2.3～3.5 a，平均病程为(3.09±0.25)a；原发性15例、继发性25例；2组患者一般资料比较，差异无统计学意义(P>0.05)，具有可比性。
1.2治疗方法
1.2.1对照组本组用输卵管介入术治疗：选择COOK公司生产的9F/5F/3F导管、0.015导丝各1个，用Ziehm8000 X光机为患者诊疗；为患者用76%泛影葡胺造影，确定病变位置后经9F导管将5F导管、白泥鳅导丝插入到间质处取出导丝，再经5F导管插进3F导管+0.015导丝，待交替前行稳定后取出导丝，以3F导管将造影剂注入，造影剂均匀弥散于盆腔时则提示复通成功，再经3F导管将香丹注射液(20 mL)注入；诊治后首次月经干净后3～7 d内做输卵管介入术，下个月经周期时做宫腔输卵管通液术1次，并注入香丹注射液(40 mL)。, http://www.100md.com(牛红萍 詹兴秀 周晓娜)
关键词：超声造影；补肾活血；输卵管性不孕
中图分类号：R271.14文献标志码：B文章编号：1007-2349(2017)12-0023-03
【Abstract】Objective： To study the clinical effect of contrast-enhanced ultrasound combined with kidney-tonifying and blood activating method on diagnosis and treatment of tubal infertility. Methods： 80 patients who were diagnosed and treated in our hospital from June 2015 to June 2016 were randomly divided into two groups， 40 cases per group. The patients in the control group were treated with tubal intervention while the patients in the observation group were treated with carbamide peroxide ultrasonic fluid plus kidney-tonifying and blood activating method. The endometrial thickness， E2 level changes and pregnancy of the two groups before and after treatment were recorded in detail. Results： The improvement of endometrial thickness and E2 level in observation group was better than that in control group and the pregnancy was better than that of the control group. The difference was statistically significant (P<0.05). Conclusion： The diagnosis and treatment of tubal infertility patients by contrast-enhanced ultrasound and kidney-invigorating and blood-activating method are good， which can fully improve the thickness of endometrium and the level of E2 after treatment， and obtain higher pregnancy rate， worthy of wide application in clinic.
【Key words】contrast-enhanced ultrasound， kidney-invigorating and blood-activating method， tubal infertility
輸卵管因素导致的不孕约占整个不孕症人群45%～55%，是引起女性不孕的首要原因[1]。急慢性盆腔炎等则是导致输卵管性不孕的常见原因，可引起输卵管阻塞、蠕动能力减弱而致不孕。输卵管性不孕是一种相对不孕，且大多为继发性不孕，通过治疗可以获得妊娠。针对输卵管性不孕的治疗，常根据输卵管阻塞部位和程度的不同采用输卵管通液、宫腔镜下输卵管插管通液、宫腹腔镜手术以及辅助生育技术等。社会不断进步，输卵管炎性不孕的临床发病率却逐年上升。在我国经济迅速发展、计划生育不断调整的今天，生育成为了大多数家庭关注的重点。面对输卵管炎性不孕的高发病率，面对输卵管性不孕，如何选择一种简便、易行、疗效可靠的诊治方法，至关重要。本文旨右探讨过氧化碳酰胺超声下通液加补肾活血大法诊治输卵管性不孕的疗效。现将结果报道如下。
1资料与方法
1.1一般资料将2015年6月—2016年6月于本院诊治的输卵管性不孕患者80例随机分为对照组与观察组。对照组40例患者中：年龄24～38岁，平均年龄为(28.16±3.42)岁；病程2～3.5 a，平均病程为(3.14±0.31)a；原发性17例、继发性23例。观察组40例患者中：年龄23～35岁，平均年龄为(27.01±3.17)岁；病程2.3～3.5 a，平均病程为(3.09±0.25)a；原发性15例、继发性25例；2组患者一般资料比较，差异无统计学意义(P>0.05)，具有可比性。
1.2治疗方法
1.2.1对照组本组用输卵管介入术治疗：选择COOK公司生产的9F/5F/3F导管、0.015导丝各1个，用Ziehm8000 X光机为患者诊疗；为患者用76%泛影葡胺造影，确定病变位置后经9F导管将5F导管、白泥鳅导丝插入到间质处取出导丝，再经5F导管插进3F导管+0.015导丝，待交替前行稳定后取出导丝，以3F导管将造影剂注入，造影剂均匀弥散于盆腔时则提示复通成功，再经3F导管将香丹注射液(20 mL)注入；诊治后首次月经干净后3～7 d内做输卵管介入术，下个月经周期时做宫腔输卵管通液术1次，并注入香丹注射液(40 mL)。, http://www.100md.com(牛红萍 詹兴秀 周晓娜)
参见：首页 > 医学版 > 医学知识 > 生殖系统 > 女性生殖系统 > 输卵管