摘要：目的 探讨乳腺癌中医证型与乳腺癌的中雌激素受体(ER)、孕激素受体(PR)表达的相关性。方法 采用常规免疫组化法检测216例临床病理诊断明确及资料完整的乳腺癌组织中的ER和PR的表达，并分为ER、PR均阴性组和ER、PR均阳性组。另外，收集所有患者的临床病理特征、舌脉及脉象。结果 ER和PR均阴性组的百分比为47.2%，ER和PR均阳性组的百分比为52.7%；ER、PR均阳性组肝郁气滞证型的比例较高，差异具有统计学意义(P<0.05)；结论 ER、PR均阳性与均阴性，两者中医证型存在不同，辨证论治可明显改善患者临床疗效，提高生存质量，为中医药在分子学领域开辟新道路。

    关键词：乳腺癌中医证型；雌激素受体；孕激素受体；免疫组化

    中图分类号：R737.9 文献标志码：A 文章编号：1007-2349(2018)11-0028-03

    【Abstract】Objective： To study the correlation between the TCM syndromes of breast cancer and the expression of estrogen receptor (ER) and progesterone receptor (PR) in breast cancer. Methods： The expressions of ER and PR in the tissues of 216 breast cancer patients with clear pathological diagnosis and complete data were detected by routine immunohistochemistry. The patients were divided into ER and PR negative groups and ER and PR positive groups. In addition ......