摘要：目的 探讨采用中药分期序贯方案治疗慢性乙肝肝纤维化的效果。方法 将120例研究对象随机分成观察组(n=60)与对照组(n=60)，对照组实施常规治疗，观察组在常规治疗基础上加用中药分期序贯方案治疗，观察2组临床疗效及治疗前后血清Ⅳ型胶原(CIV)、层黏连蛋白(LN)、透明质酸(HA)及补体C3水平变化。结果 观察组治疗总有效率为93.33%，明显高于对照组76.67%(P<0.05);治疗3个疗程后，2组患者CIV、LN、HA及补体C3水平均较治疗前降低，但观察组降低幅度优于对照组(P<0.05)。结论 针对慢性乙肝肝炎肝纤维化，在常规治疗的基础上实施中药分期序贯方案治疗，可实现疾病的逆转，降低体内补体C3水平，值得推广。

    关键词：中药分期序贯;慢性乙型肝炎;肝纤维化;逆转;补体C3

    中图分类号：R285.6 文献标志码：A 文章编号：1007-2349(2019)08-0021-03

    【Abstract】Objective： To study the effect of sequential Chinese medicine staging on the treatment of liver fibrosis patients with chronic hepatitis B. Methods： 120 subjects were randomly divided into an observation group (n=60) and a control group (n=60). The control group was given routine treatment and the observation group was treated with traditonal Chinese medicine staging sequence on the basis of routine treatment. The changes of clinical effects and serum levels of type IV collagen (CIV) ......