CK20检测直肠癌系膜根部淋巴结微转移情况及其临床意义
doi:10.3969/j.issn.1007-614x.2014.2.68摘 要 目的:探讨41例直肠癌92枚系膜根部淋巴结微转移状态,以及淋巴结微转移对淋巴结分期的影响。方法:对41例直肠癌92枚系膜根部淋巴结行间断连续切片结合细胞角蛋白20抗体免疫组织化学染色方法检测淋巴结微转移,并进行统计学处理。结果:41例直肠癌患者92枚肠系膜下动脉根部淋巴结发生微转移9例11枚。结论:CK免疫组化技术可以显著提高直肠癌淋巴结转移的检出率,有助于更准确地进行临床病理分期,为直肠癌全系膜切除(TME)提供理论依据。
关键词 淋巴结微转移 细胞角蛋白20 直肠癌
Using CK20 to detect Lymph node micrometastasis of Mesenteric root of rectal cancer and its clinical significance
Meng Zhaoqing
Second Department of general surgery of Dandong Central Hospital of Liaoning Province,118000
Abstract Objective:To explore the 92 Mesenteric root Lymph node micrometastasis of 41 cases and the effect of Lymph node micrometastasis on staging of lymph nodes.Methods:We detected 92 Mesenteric root Lymph node micrometastasis of 41 cases by continuous sectioning and cytokeratin 20 antibody immunohistochemical staining method.The results were statistically analyzed.Results:11 pieces of 9 cases had Lymph node micrometastasis in these patients.Conclusion:CK immunohistochemical technique can significantly improve the detection rate of lymph node metastasis of rectal cancer ......
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