甘精胰岛素联合瑞格列奈治疗初诊2型糖尿病的疗效观察
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doi:10.3969/j.issn.1007-614x.2014.11.18
摘 要 目的:探讨甘精胰岛素联合瑞格列奈治疗初诊2型糖尿病的临床疗效。方法:收治初诊T2DM患者40例,经甘精胰岛素联合瑞格列奈治疗16周,比较治疗前后空腹血糖(FBG)、餐后2小时血糖(PBG)、糖化血红蛋白(HbA1C)的差异,同时观察总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL-C)、血常规、肝、肾功能的变化及体重指数(BMI),低血糖的药物不良反应。结果:治疗12周后,与治疗前相比,FBG、PBG、HbA1C均降低(P<0.05),TC、TG、LDL-C,血常规、肝、肾功能、BMI与治疗前相比差异无统计学意义(P>0.05),有低血糖反应3例次。结论:甘精胰岛素联合瑞格列奈治疗初诊T2DM患者,能使血糖下降明显,且不良反应轻微、安全。
关键词 甘精胰岛素 瑞格列奈 2型糖尿病
Curative effect observation of insulin glargine combined with repaglinide in the treatment of newly diagnosed type 2 diabetes
Huang Ruihua
Department of Endocrinology,the People's Hospital of Pizhou City,Jiangsu 221300
Abstract Objective:To investigate the clinical efficacy of insulin glargine combined with repaglinide in the treatment of newly diagnosed type 2 diabetes.Methods:40 newly diagnosed patients with T2DM were selected ......
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