【摘要】目的:探讨减少川崎病发生冠状动脉病变的治疗方法。方法:用川芎嗪结合西药治疗川崎病92例,观察临床表现的消失时间和冠状动脉病变的发生率。结果:川芎嗪结合西药治疗川崎病,冠状动脉病变发生率为10.4%,纯西药组29.5%,有显著差异(P<0.05),而临床表现的消退时间无明显差异性。结论:川芎嗪对减少川崎病发生冠状动脉病变有显著的治疗和预防作用。

    【关键词】川崎病;冠状动脉;川芎嗪

    【中图分类号】R2-031【文献标识码】A【文章编号】1007-8517(2010)10-009-2

    [Abstract]:Objective To find the method to reduce the coronary artery lesion in Kawasaki disease.Methods Ninty-two patients with Kawasaki disease were combined treated by tetramethyl pyrazine and western medicine,observed curative effect. Results In tetramethyl pyrazine combined with western medicine group,coronary artery lesion incidence was 10.4%,while in pure western medicine group,the incidence was 29.5%. There are significant differences (P <0.05). But the fade time of clinical manifestations showed no obvious differences. Conclusion tetramethyl pyrazine is effective to reduce the incidence of coronary artery lesion.

    [Key words]:Kawasaki disease;coronary artery;tetramethyl pyrazine

    川崎病(kawasaki disease,KD)又名皮肤粘膜淋巴结综合征,是一种原因不明确的小儿常见自身免疫性血管炎综合征 ......