中西医结合治疗终末期癌痛40例临床观察(1)
【摘 要】 目的：观察中西医结合疗法治疗终末期癌痛的临床疗效。方法：选取80例终末期癌症患者且NRS疼痛评分均在4分以上。根据治疗方法随机分成采用吗啡肌注治疗癌痛的对照组与吗啡肌注联合中药硬膏外敷治疗的观察组各40例。观察两组疼痛缓解情况。结果：治疗后观察组总有效率为95.0%，对照组总有效率为77.5%，两组比较差异有统计学意义(P<0.05)；两组不良反应差异无统计学意义(P>0.05)。结论：中西医结合疗法可有效缓解终末期癌痛，改善患者的生存质量，值得临床推广应用。
【关键词】 中西医结合；终末期癌疼；吗啡；中药硬膏；疗效
【中图分类号】R2-031 【文献标志码】 A 【文章编号】1007-8517(2017)09-0128-03
Analysis of the Clinical Effect of Combining Traditional Chinese and Western Medicine Therapy in the Treatment of End-stage Cancer Pain
HE Zhengqiu CHEN Juan ZHANG Dingrong WANG Peishu LIU Jianjun XIE Liqiong DONG Wei
Department of oncology， Guangyuan Hospital of traditional Chinese medicine，Cangxi 628400，China
Abstract：Objective To analyze the clinical effect of combined therapy of traditional Chinese and Western medicine in the treatment of end stage cancer.Methods Selected 80 cases of cancer patients in our hospital were randomly selected and NRS pain scores were above 4. According to the methods of treatment were randomly divided into control group with intramuscular injection of morphine in the treatment of cancer pain 40 cases， the observation group with intramuscular injection of morphine combined with Chinese hard plaster treatment 40 cases. The pain relief of the two groups were observed.Results The two groups by their respective treatment regimen in the treatment of end-stage cancer patients， the total efficiency of the observation group 95%. Control group the total effective rate was 77.5%，and there was no significant difference between the two groups (P>0.05).Conclusion Combination of traditional Chinese and Western medicine therapy can relief terminal cancer pain， effectively improve the quality of life of patients with end stage cancer， it is worth promoting.
Keywords：Combination of Traditional Chinese and Western Medicine； End-stage Cancer Pain； Morphine； Traditional Chinese Medicine Plaster； Curative Effect
癌癥终末期会出现较为严重的癌痛症状，严重影响患者生存质量。传统肌注吗啡虽然能在一定程度上缓解疼痛，但存在一定毒性，长时间大量使用还会造成耐药性，难以控制用量[1]。相关研究[1]显示，在吗啡治疗的基础上加用中药外敷能够有效提高癌痛缓解率，笔者为进一步明确中西医结合疗法对于终末期癌症的临床治疗效果，随机选取80例终末期癌症患者，分为采用吗啡肌注治疗癌痛的对照组，与吗啡肌注联合中药硬膏外敷治疗的观察组，观察两组的疼痛缓解情况，具体报告如下。
1 资料与方法
1.1 一般资料 选取2014年6月到2016年6月我院收治的癌症患者80例作为研究对象。患者NRS疼痛评分均在4分以上。分成采用吗啡肌注治疗癌痛的对照组与吗啡肌注联合中药硬膏外敷治疗的观察组各40例。其中对照组男性22例，女性18例，年龄29～80岁，平均年龄(53.96±7.82)岁。其中肺癌10例，消化道恶性肿瘤19例，头颈部恶性肿瘤6例，妇科恶性肿瘤4例，其他1例。观察组男性23例，女性17例，年龄28～81岁，平均年龄(54.42±8.64)岁。其中肺癌9例，消化道恶性肿瘤18例，头颈部恶性肿瘤5例，妇科恶性肿瘤6例，其他2例。两组一般资料比较差异无统计学意义(P>0.05)，具有可比性。所有患者均签署知情同意书。, 百拇医药(何正秋 陈娟 张定荣 王培术 刘建军 谢丽琼 董玮)
【关键词】 中西医结合；终末期癌疼；吗啡；中药硬膏；疗效
【中图分类号】R2-031 【文献标志码】 A 【文章编号】1007-8517(2017)09-0128-03
Analysis of the Clinical Effect of Combining Traditional Chinese and Western Medicine Therapy in the Treatment of End-stage Cancer Pain
HE Zhengqiu CHEN Juan ZHANG Dingrong WANG Peishu LIU Jianjun XIE Liqiong DONG Wei
Department of oncology， Guangyuan Hospital of traditional Chinese medicine，Cangxi 628400，China
Abstract：Objective To analyze the clinical effect of combined therapy of traditional Chinese and Western medicine in the treatment of end stage cancer.Methods Selected 80 cases of cancer patients in our hospital were randomly selected and NRS pain scores were above 4. According to the methods of treatment were randomly divided into control group with intramuscular injection of morphine in the treatment of cancer pain 40 cases， the observation group with intramuscular injection of morphine combined with Chinese hard plaster treatment 40 cases. The pain relief of the two groups were observed.Results The two groups by their respective treatment regimen in the treatment of end-stage cancer patients， the total efficiency of the observation group 95%. Control group the total effective rate was 77.5%，and there was no significant difference between the two groups (P>0.05).Conclusion Combination of traditional Chinese and Western medicine therapy can relief terminal cancer pain， effectively improve the quality of life of patients with end stage cancer， it is worth promoting.
Keywords：Combination of Traditional Chinese and Western Medicine； End-stage Cancer Pain； Morphine； Traditional Chinese Medicine Plaster； Curative Effect
癌癥终末期会出现较为严重的癌痛症状，严重影响患者生存质量。传统肌注吗啡虽然能在一定程度上缓解疼痛，但存在一定毒性，长时间大量使用还会造成耐药性，难以控制用量[1]。相关研究[1]显示，在吗啡治疗的基础上加用中药外敷能够有效提高癌痛缓解率，笔者为进一步明确中西医结合疗法对于终末期癌症的临床治疗效果，随机选取80例终末期癌症患者，分为采用吗啡肌注治疗癌痛的对照组，与吗啡肌注联合中药硬膏外敷治疗的观察组，观察两组的疼痛缓解情况，具体报告如下。
1 资料与方法
1.1 一般资料 选取2014年6月到2016年6月我院收治的癌症患者80例作为研究对象。患者NRS疼痛评分均在4分以上。分成采用吗啡肌注治疗癌痛的对照组与吗啡肌注联合中药硬膏外敷治疗的观察组各40例。其中对照组男性22例，女性18例，年龄29～80岁，平均年龄(53.96±7.82)岁。其中肺癌10例，消化道恶性肿瘤19例，头颈部恶性肿瘤6例，妇科恶性肿瘤4例，其他1例。观察组男性23例，女性17例，年龄28～81岁，平均年龄(54.42±8.64)岁。其中肺癌9例，消化道恶性肿瘤18例，头颈部恶性肿瘤5例，妇科恶性肿瘤6例，其他2例。两组一般资料比较差异无统计学意义(P>0.05)，具有可比性。所有患者均签署知情同意书。, 百拇医药(何正秋 陈娟 张定荣 王培术 刘建军 谢丽琼 董玮)