冠状动脉病变严重程度与颈动脉粥样硬化的相关性研究(2)
冠状动脉造影是评价冠状动脉血管内径的狭窄程度的方法,而超声是评价血管壁的结构 ,在冠状动脉造影发现冠状动脉狭窄发生有意义的病变(通常≥50%)前,外周动脉和冠状 动脉均已发生血管重构,除血管内膜有不同程度增厚外,其外径也出现扩张,故冠状动脉造 影难以辨别早期冠状动脉硬化[8]。可见,超声检查外周动脉可早期发现动脉粥样 硬化和 动脉内膜增厚,因外周动脉的粥样硬化和IMT增厚与冠状动脉病变严重程度呈明显的相关性 ,所以,对颈动脉IMT明显增厚的患者进行早期临床干预如口服他汀类调脂药物,对预防冠 心病的发生和发展有重要临床意义。
参考文献:
[1] CLEMENT D L, BOCCALON H, Dormandy J, et al. A clinicalapproach to the management of the patients with coronary and carotid artery dise ase who presents with leg ischemia[J].In Angiol, 2000,19:97-125.
[2] 许竹平,赵水平,范萍.超声测量颈动脉内膜中层厚度与颈动脉斑块的关 系[J].中国动脉硬化杂志,2000,8(2):165-168.
[3] 曹志友,任旷.颈动脉超声与冠状动脉造影对颈动脉粥样硬化的评估作用 [J].中国临床康复,2004,8(15):2846-2847.
[4] TANAKA H, NISHINOM. Progression carotid ather-oscleros isin Japanese patients with coronary disease[J].Stroke,1992,23(7):946-951.
[5] GOSTOMZYK J G, HELLER W D, GERHARDT P, et al. Dscan ultrasou nd examination o f the carotid arteries with in a representative population(MONICAProjectAug sburg)[J]. Klin Wochenschr, 1988, 66(11):58-65.
[6] TAKASHI W, TSUTOMU F, KENTARO F.Ultra-sonic correlates of c ommon carotid a therosclerosis in patients with coronary artery disease[J].Anglology,2002,53( 2):177-183.
[7] SPENCE J D. Ultrasound measurement of carotid plaque as a su rroga te outcome for coronary artery disease[J].Am J Canliol, 2002, 21:10B-16B.
[8] GLAORV S, ZARINS C, GIDDENS D P, et al. Hemo-dynamic and at heroscle rosis: insights and perspectives gained from studies of human arteries[J]. Ar ch Pathol Lab Med,1988,112:1018.
(收稿日期: 2009-04-20)
[责任编辑 王慧瑾 邓德灵], http://www.100md.com(陆兆华 叶少武 卢 谦 李以容 彭晓燕)
参考文献:
[1] CLEMENT D L, BOCCALON H, Dormandy J, et al. A clinicalapproach to the management of the patients with coronary and carotid artery dise ase who presents with leg ischemia[J].In Angiol, 2000,19:97-125.
[2] 许竹平,赵水平,范萍.超声测量颈动脉内膜中层厚度与颈动脉斑块的关 系[J].中国动脉硬化杂志,2000,8(2):165-168.
[3] 曹志友,任旷.颈动脉超声与冠状动脉造影对颈动脉粥样硬化的评估作用 [J].中国临床康复,2004,8(15):2846-2847.
[4] TANAKA H, NISHINOM. Progression carotid ather-oscleros isin Japanese patients with coronary disease[J].Stroke,1992,23(7):946-951.
[5] GOSTOMZYK J G, HELLER W D, GERHARDT P, et al. Dscan ultrasou nd examination o f the carotid arteries with in a representative population(MONICAProjectAug sburg)[J]. Klin Wochenschr, 1988, 66(11):58-65.
[6] TAKASHI W, TSUTOMU F, KENTARO F.Ultra-sonic correlates of c ommon carotid a therosclerosis in patients with coronary artery disease[J].Anglology,2002,53( 2):177-183.
[7] SPENCE J D. Ultrasound measurement of carotid plaque as a su rroga te outcome for coronary artery disease[J].Am J Canliol, 2002, 21:10B-16B.
[8] GLAORV S, ZARINS C, GIDDENS D P, et al. Hemo-dynamic and at heroscle rosis: insights and perspectives gained from studies of human arteries[J]. Ar ch Pathol Lab Med,1988,112:1018.
(收稿日期: 2009-04-20)
[责任编辑 王慧瑾 邓德灵], http://www.100md.com(陆兆华 叶少武 卢 谦 李以容 彭晓燕)