摘要目的:观察伸展作用后皮肤超微结构的变化。方法:取4只体重约20kg的猪为实验动物,分别对伸展作用侧及对照侧皮肤标本进行扫描和透射电镜观察。结果:扫描电镜观察伸展皮肤的胶原纤维自身卷曲状态明显减轻,多数纤维沿着伸展力的方向排列,纤维未见断裂表现。透射电镜见伸展作用后表皮细胞层次增加,间隙增宽,真皮层胶原纤维排列整齐紧密,成纤维细胞功能活跃,胶原纤维结构未受损害。结论:皮肤伸展术是一种有效、安全的方法。

    关键词 皮肤伸展术 超微结构 扫描电镜 透射电镜

    周黎安,男,1964年生,1992年第四军医大学口腔医学院硕士研究生毕业,1996年在医科院整形外科医院进修,现为解放军451医院美容整形外科主治医生,兼任本刊编辑,皮肤伸展器专利发明人,获军队科技进步三等奖一项,发表论文16篇,参编书籍二本。主持空军重点科研项目一项。

    THE ULTRAMICROSTRUCTURAL CHANGES OF THE STRETCHED SKIN

    Zhou Lian Guo Shuzhong Li Zun et al

    Depart of Plastic surgery, Chinese PLA 451 Hospital, (Xi’an710054)

    Abstract Objective: The study was designed to investigate the ultramicrostructural changes of the s retched skin. Methods: On 4 Pigs, stretched skin was compared with non-stretched control skin from the opposite side of the animal. The specimens were observed with scanning electron microscopy (SEM) and transmission electron microscopy(TEM). Results: The collagen bundles became more aligned and compact. This alignment was along the direction of the loading force applied to the skin. The collagen fiber was normal. The epidermal cell layers were increase. The distant between cells became large. More active fibroblasts with increased rough endoplasmic reticulum、 mitochodrion and intracellular pre collagen filaments were seen in stretched skin dermis. Conclusion: The skin stretching technique was a safe and useful technique in aiding the closure of large defects. ......