皮瓣受区床与缺血-再灌注皮瓣成活的关系

http://www.100md.com 2000年12月1日《中国美容医学》 2000年第6期

     曹景敏鲁开化郭树忠

    (第四军医大学西京医院整形外科中心西安710032)

    [摘要] 目的:探讨皮瓣受区床对缺血-再灌注皮瓣成活的影响,重视受区床的营养性作用。方法:40只大鼠分成A组(皮瓣下不置硅胶膜)、B组(皮瓣下置硅胶膜后再缝合)。阻断腹壁浅血管1h、6h、10h及完全切断腹壁浅血管,观测不同时段皮瓣温度及组织病理改变,7天时计算皮瓣成活面积。结果:皮瓣温度、皮瓣成活面积及组织病理学改变阻断血管1hA、B组无明显差别,阻断6h、10h及完全切断血管两组间有显著差别。A组阻断10h与完全切断血管两组间皮瓣成活面积很相近。A组完全切断血管后真皮下组织见白细胞大量聚积。结论:皮瓣受区床对缺血-再灌注皮瓣成活起营养作用。白细胞可损害这种营养性作用。

    [关键词] 皮瓣受区床缺血-再灌注成活面积

    [中图分类号]R622+2 [文献标识码]A [文章编号]1008-6455(2000)06-0410-03

    THE RELATIONSHIP BETWEEN THE RECIPIENT BED VASCUSARITY

    AND VIABILITY OF ISCHEMIC-REPERFUSION FLAP

    CAO Jing-min LU Kai-hua GUO Shu-zhongDepart.of Plastic Surgery,Xijing Hospital, the Fourth Military Medical University(Xian 710032)[Abstract] Objective:To study the relationship between recipient bed vascularity and the viability of ischemic-reperfusion flap,highlight the importance of recipient bed nourshment. Methods:40 rats were divided into A (no silicone sheet implanted between flap and recipient bed)and B group (silicone interposed between flap and recipient bed).Different superficial abdomenvessels occlusion time(1h,6h,10h and permanent divided,respectively)was made,and flap temperature and the histopathology was studied on time.Flap survival area were measured 7 days postoperatively. Result:No significant difference of flap temperature and histopathology were found between A and B for 1h ischemia flap.but significant differences were showed for 6h,10h and permanent ischemia flap .Interestingly,it appeared the same flap surrival area between 10h and permenent ischemia in A groups,and lots of leukocyter were deposited on subcutaneous layer. Conclusion:Recipient bed vascularity have nourishing effect on ischemic reperfusion flaps.Leukocytes may damage this effect.[Key words] Flap Recipient bed Ischemia-reperfusion Viability ......

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