[摘要]目的：探讨VEGF对血管及软组织长入多孔聚乙烯支架的影响。方法：制作多孔聚乙烯支架置入动物体内的模型后，随机分成2组：第一组应用VEGF；第二组为对照组(不给任何药物)。术后第7天、第14天取出支架，做组织学分析观察毛细血管及肉芽组织长入状况。结果：应用VEGF组血管及肉芽组织长入孔隙迅速，而对照组长入缓慢，有显著性差异。结论：血管内皮生长因子可促进血管及软组织长入多孔聚乙烯支架，从而加强了该支架的稳定性，促进植入效果。

    [关键词]耳支架；血管内皮生长因子(VEGF)；耳再造

    [中图分类号]Q813[文献标识码]A[文章编号]1008-6455(2008)08-1178-03

    The effects of VEGF on blood vessels and soft tissues growing into the porous polyethylene pivoting helix framework

    TIAN Li-liang1,DIAO Zhi-yong2

    (1.Department of Plastic And Cosmetic Surgery, the Fifth Affiliated Hospital of harbin Medical University, Daqing 164300,Heilongjiang,China; 2. Department of Plastic and Cosmetic Surgery,the Fifth Affiliated Hospital of harbin Medical University,Harbin 150001,Heilongjiang ......