[摘要]目的：观察A型肉毒毒素治疗面部皱纹的运用效果。方法：对以面部美容为目的的300例患者应用A型肉毒毒素定点、定量注射治疗，注射点均匀、对称分布于面部肌肉层。其中包括额部皱纹、鱼尾纹、眉间皱纹、下睑纹、鼻唇沟纹。结果：300例患者行A型肉毒毒素治疗后显效者234例(占78%)，有效者66例(占22%)，无效者为0例。结论：A型肉毒毒素在治疗面部皱纹确切有效，操作简便、易行，无痛苦，不影响工作，易于推广。

    [关键词]A型肉毒毒素；面部皱纹

    [中图分类号]R622 [文献标识码]A [文章编号]1008-6455(2009)02-0161-02

    Experience on applying botulinum toxin type A to treat facial wrinkle for300 examples

    TIAN Xia,LI Yun,ZHONG Wen-hui,GOU Qing-fen,CHEN Fang,YAO Cui-ying,YANG Zhe,SHAO Fang

    (Departerment of Plastic Surgery,the Affiliated Hospital of Wuhan Science and Technology University, Wuhan 430064,Hubei,China)

    Abstract：ObjectiveTo observe the botulinum toxin type A treatment of facial wrinkles using the results.Methodsbeauty in the face for the purpose of the 300 cases of patients with Botulinum Toxin Type A fixed-point, quantitative injection, the injection point uniform, facial symmetry in the distribution of muscle layer. These include the Department of the amount of wrinkles, Yu Weiwen, glabella wrinkles, lower profile, nasolabial fold pattern.Results300 cases of patients with botulinum toxin type A treatment effect were 234 cases (78%), 66 cases were effective (22%), 0 case was null and void.ConclusionsA-Botox in the treatment of facial wrinkles precise and effective,simple,easy,painless,non-impact,easy-to-promotion. ......