Ezrin和AQP3在皮肤鳞状细胞癌中表达的研究(2)
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综上所述，Ezrin与AQP3蛋白的表达可能与SCC的发生及恶性程度有关，联合检测2者可能为SCC诊断提供理论依据。
[参考文献]
[1]Krishnan K,Bruce B,Hewitt S,et al. Ezrin mediates growth and survival in Ewing's sarcoma through the AKT/mTOR,but not the MAPK,signaling pathway[J].Clin Exp Metastasis,2006, 23(3-4):227-236.
[2]Takata K,Matsuzaki T,Tajika Y. Aquaporins: water channel proteins of the cell membrane [J]. Prog Histochem Cytochem,2004,39:l-83.
[3]Sougrat R,Morand M,Gondran C,et al. Functional expression of AQP3 in human skin epidermis and reconstructed epidermis [J]. Invest Dermatol,2O02,118(4):678-685.
[4]Preston GM,Agre P. Molecular cloning of the red cell integral protein of Mr28, 000: A member of an ancient channel family [J]. Proc Natl Acad Sci USA,1991,88:11110-11114.
[5]Bedford JJ,Leader JP,Walker RJ,et al. Aquaporin expression in normal human kidney and in renal disease[J].Am Soc Nephrol,2003,14:2581-2587.
[6]KingLS,YasuiM,Agre P. Aquaporins in health and disease [J]. Mol Med Today,2000,6(2):60-65.
[7]Mccoy E,Sontheimer H. Expression and function of water channels (aquaporins) in migrating m alignant astrocytes [J]. Glia,2007Aug1,55(10):1034-1043.
[收稿日期]2011-02-26[修回日期]2011-04-16
编辑/张惠娟
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