正畸釉质脱矿的FTIR研究(1)
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[摘要]目的：探讨青少年固定正畸治疗后牙面脱矿与唾液之间的关联，为牙面脱矿的风险预测及揭示脱矿原因提供参考。方法：选取符合条件的30名实验对象(矫治中15名出现脱矿，15名未脱矿)，使用傅立叶红外检测方法检测其治疗前、治疗结束时的唾液样本并获得光谱。选取光谱图中具有代表意义的V1～V1010个位点，利用Logistic统计学分析牙面脱矿现象与10个位点的相对吸收度及相应化学键。结果：建立了回归方程， V1、V2、V4、V7与脱矿呈正相关，V3、V5、V6、V8、V9、V10与脱矿呈负相关。结论：所建回归方程可用于脱矿风险预测，正畸后发生的牙面脱矿与患者唾液内10种化学官能团存在线性相关。
[关键词]牙釉质脱矿；唾液；FTIR；Logistic线性回归分析
[中图分类号]R783.5 [文献标识码]A [文章编号]1008-6455(2012)02-0261-03
Study on the fourier transform infrared detection of saliva of orthodontic patients
XU Yi-fei1,QI Kun2,LIU Zheng3,ZOU Min1
(1.Department of Orthodontics, Stomatology Hospital,Xi`an Jiaotong University,Xi'an 710004,Shaanxi,China;2.Department of Orthodontics Tianjin Stomatology Hospital;3. Department of Oral Medicine,Stomatology Hospital,Xi'an Jiaotong University)
Abstract: Objective To predict risk of orthodontic tooth surface demineralization and reveal the cause of demineralization,saliva correlation between Fourier transform infrared spectroscopy was study. Methods Selected the 30 subjects, in which 15 patients occurred enamel decalcification and 15 didn't occur enamel decalcification,and obtain Fourier transform infrared spectroscopy. Then we selected 10 sites which is significant of the spectrum represented. Studying Forrier transform of the patients before treatment and after treatment and then using the method of Logestic Statistics to analyse the relationship between the enamel decalcification and saliva composition. Results Regression equation was established,in the ten sites,V1,V2,V4,V7 were positively correlated to demineralization, and V3、V5、V6、V8、V9、V10 were a negative correlation to demineralization. Conclusions The main component of saliva has a linear correlation with enamel demineralization,regression equation can predict the risk of demineralization reference.
Key words:Enamel decalcification; Saliva; FTIR; Logistic Linear regression
错颌畸形患病率67.82%[1]，多使用固定矫治技术进行治疗，而固定矫治后的牙面脱矿发生率20%～60%，是临床上最常见的并发症之一。脱矿表现为釉质表面呈现白垩色，甚至釉质缺损，对患者牙面的美观和健康造成了一定的影响[2-3]，目前主要是依靠患者自身唾液的再矿化改善症状，而正畸医生主要依赖于矫治期间使用含氟制剂进行预防[4]，总之，无良好的治疗方法。有关唾液与脱矿病因的研究较多，但主要基于唾液某种单一成分与脱矿之间的关系而展开的[5-6] ......
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