化脓性大汗腺炎的手术治疗(3)
在HS好發部位中,腋窝是对外形和功能修复要求最高的。直接植皮者局部凹陷明显,可出现色素沉着、皮片挛缩、瘢痕增生,无论是外形还是功能均不能与皮瓣/肌皮瓣相比。源于侧胸和背部的皮瓣是修复腋窝创面的两种常见的选择。侧胸皮瓣尽管质地与腋窝相似,但无论采用异位还是推进皮瓣都会在腋顶部对上臂产生不同程度的牵拉。而源于背部的各种皮瓣(肩胛皮瓣、背阔肌肌皮瓣、胸背动脉穿支皮瓣),虽不会对上臂产生牵拉,但修复后腋窝往往比较臃肿,也会影响术后的外形和功能,尤其是一些肥胖的患者。为解决这一问题,采用了背阔肌肌瓣联合游离植皮的方法,其优点如下:①背阔肌血运丰富,对于可能残留的感染可起到生物清除的作用;②背阔肌面积大,可修复大面积缺损,供区可直接缝合无需植皮;③肌肉柔软又有一定的厚度,修复腋窝HS切除后的创面,既不会使腋窝过度凹陷又不会使其过度臃肿,外形美观;④在肌瓣上可采用厚、中厚皮片移植,降低了术后皮片收缩的可能,加以术后功能锻炼,患者肩关节活动并无明显障碍。
总之,HS是一种慢性感染性皮肤病变,手术彻底切除病变的皮肤及皮下组织是治疗进展期HS的唯一方法。在条件允许的情况下,病灶切除后首选皮瓣或肌皮瓣修复,尤其对于外露或功能部位的创面。背阔肌肌瓣联合游离植皮术后外形、功能的恢复均令人满意,是修复腋窝HS术后创面的一种较好的方法。
, http://www.100md.com
[参考文献]
[1]Jemec GB.Hidradenitis Suppurativa[J].N Engl J Med,2012,366(2):158-164.
[2]Revuz JE,Canoui-Poitrine F,Wolkenstein P,et al.Prevalence and factors associated with hidradenitis suppurativa: results from two case–control studies[J].J Am Acad Dermatol,2008,59(4):596-601.
[3]Mebazaa A,Ben Hadid R,Cheikh Rouhou R,et al.Hidradenitis suppurativa: a disease with male predominance in Tunisia[J].Acta Dermatovenerol Alp Panonica Adriat,2009,18(4):165-172.
, 百拇医药
[4]赵义瑞,辛素文.治疗大汗腺炎32例临床小结[J].中国肛肠病杂志,2001,21(5):43.
[5]Nazary M,van der Zee HH,Prens EP,et al.Pathogenesis and pharmacotherapy of Hidradenitis suppurativa[J].Eur J Pharmacol,2011,672(1-3):1-8.
[6]Yazdanyar S,Jemec GB.Hidradenitis suppurativa: a review of cause and treatment[J].Curr Opin Infect Dis,2011,24(2):118-123.
[7]Poli F,Wolkenstein P,Revuz J.Back and face involvement in hidradenitis suppurativa[J].Dermatology,2010,221(2):137-141.
, 百拇医药
[8]Syed ZU,Hamzavi IH.Atypical hidradenitis suppurativa involving the posterior neck and occiput[J].Arch Dermatol,2011,147(11):1343-1344.
[9]Kagan RJ,Yakuboff KP,Warner P,et al.Surgical treatment of hidradenitis suppurativa: A 10-year experience[J].Surgery,2005,138(4):734-741.
[10]Losanoff JE,Sochaki P,Khoury N,et al.Squamous cell carcinoma complicating chronic suppurative hydradenitis[J].Am Surg,2011,77(11):1449-1453.
, http://www.100md.com
[11]Jackman RJ.Hidradenitis suppurativa: diagnosis and management of perianal manifestation[J].Proc R Soc Med,1959,52(Suppl):110-112.
[12]Beshara MA.Hidradenitis suppurativa: A clinician's tool for early diagnosis and treatment[J].Adv Skin Wound Care,2010,23(7):328-332.
[13]Gao M,Wang PG,Cui Y,et al.Inversa acne (hidradenitis suppurativa): a case report and identification of the locus at chromosome 1p21.1-1q25.3[J].J Invest Dermatol,2006,126(6):1302-1306.
[14]Rambhatla PV,Lim HW,Hamzavi l.A systematic review of treatments for hidradenitis suppurativa[J].Arch Dermatol,2012,148(4):439-446., 百拇医药(柴密 曾玮 杨红岩 郭伶俐 乌兰哈斯 韩岩)
总之,HS是一种慢性感染性皮肤病变,手术彻底切除病变的皮肤及皮下组织是治疗进展期HS的唯一方法。在条件允许的情况下,病灶切除后首选皮瓣或肌皮瓣修复,尤其对于外露或功能部位的创面。背阔肌肌瓣联合游离植皮术后外形、功能的恢复均令人满意,是修复腋窝HS术后创面的一种较好的方法。
, http://www.100md.com
[参考文献]
[1]Jemec GB.Hidradenitis Suppurativa[J].N Engl J Med,2012,366(2):158-164.
[2]Revuz JE,Canoui-Poitrine F,Wolkenstein P,et al.Prevalence and factors associated with hidradenitis suppurativa: results from two case–control studies[J].J Am Acad Dermatol,2008,59(4):596-601.
[3]Mebazaa A,Ben Hadid R,Cheikh Rouhou R,et al.Hidradenitis suppurativa: a disease with male predominance in Tunisia[J].Acta Dermatovenerol Alp Panonica Adriat,2009,18(4):165-172.
, 百拇医药
[4]赵义瑞,辛素文.治疗大汗腺炎32例临床小结[J].中国肛肠病杂志,2001,21(5):43.
[5]Nazary M,van der Zee HH,Prens EP,et al.Pathogenesis and pharmacotherapy of Hidradenitis suppurativa[J].Eur J Pharmacol,2011,672(1-3):1-8.
[6]Yazdanyar S,Jemec GB.Hidradenitis suppurativa: a review of cause and treatment[J].Curr Opin Infect Dis,2011,24(2):118-123.
[7]Poli F,Wolkenstein P,Revuz J.Back and face involvement in hidradenitis suppurativa[J].Dermatology,2010,221(2):137-141.
, 百拇医药
[8]Syed ZU,Hamzavi IH.Atypical hidradenitis suppurativa involving the posterior neck and occiput[J].Arch Dermatol,2011,147(11):1343-1344.
[9]Kagan RJ,Yakuboff KP,Warner P,et al.Surgical treatment of hidradenitis suppurativa: A 10-year experience[J].Surgery,2005,138(4):734-741.
[10]Losanoff JE,Sochaki P,Khoury N,et al.Squamous cell carcinoma complicating chronic suppurative hydradenitis[J].Am Surg,2011,77(11):1449-1453.
, http://www.100md.com
[11]Jackman RJ.Hidradenitis suppurativa: diagnosis and management of perianal manifestation[J].Proc R Soc Med,1959,52(Suppl):110-112.
[12]Beshara MA.Hidradenitis suppurativa: A clinician's tool for early diagnosis and treatment[J].Adv Skin Wound Care,2010,23(7):328-332.
[13]Gao M,Wang PG,Cui Y,et al.Inversa acne (hidradenitis suppurativa): a case report and identification of the locus at chromosome 1p21.1-1q25.3[J].J Invest Dermatol,2006,126(6):1302-1306.
[14]Rambhatla PV,Lim HW,Hamzavi l.A systematic review of treatments for hidradenitis suppurativa[J].Arch Dermatol,2012,148(4):439-446., 百拇医药(柴密 曾玮 杨红岩 郭伶俐 乌兰哈斯 韩岩)