IL-1β经NK-kB通路对牙周膜干细胞成骨成分调控的机制研究(4)
综上所述,炎症因子IL-1β可激活NF-kB信号通路,并且可抑制牙周膜干细胞向成骨分化;对NF-kB信号通路抑制后能够明显逆转IL-1β导致的干细胞成骨分化能力降低。[参考文献]
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