方慧 陈滨

    [摘要]目的：探究調Q脉冲激光和两种波段强脉冲光治疗面部痤疮后红斑及色素沉着的临床疗效和安全性。方法：选取2018年3月-2020年3月笔者医院门诊收治的面部痤疮后红斑及色素沉着患者80例，根据治疗方式的不同分为调Q脉冲激光组(接受调Q脉冲激光治疗，n=33)和强脉冲光组(接受两种波段的强脉冲光治疗，n=47)。对两种治疗方式的安全性进行评估，比较两组患者的临床疗效、治疗前后的红斑及色素沉着情况及皮肤生理指标变化水平。结果：调Q脉冲激光组的治疗总有效率为93.94%，强脉冲光组的治疗总有效率为82.98%，两组治疗总有效率比较无明显差异(P>0.05);治疗后，两组患者的红斑及色素沉着程度较治疗前明显下降(P0.05);治疗后，两组患者的皮肤pH值、TEWL均明显下降，角质层含水量明显上升(P0.05);治疗期间，两组患者出现紧绷感、轻度毛细血管扩张、紫癜等不良反应，未使用任何药物，症状均于术后1～7d内消失。治疗第2、3次，调Q脉冲激光组患者的VAS评分明显低于强脉冲光组(P0.05)。结论：调Q脉冲激光与多波段联合强脉冲光在治疗面部痤疮后红斑及色素沉着方面疗效相当，安全性较高，均可明显改善患者的红斑及色素沉着情况，且无明显不良反应，但调Q脉冲激光在改善患者红斑程度和皮肤屏障功能方面优于多波段联合强脉冲光。

    [关键词]寻常痤疮;红斑;色素沉着;调Q脉冲激光;强脉冲光

    [中图分类号]R758.73+3? ? [文献标志码]A? ? [文章编号]1008-6455(2021)05-0090-04

    Curative Effect of Q-switched Pulse Laser and Intensive Pulsed Light on Facial Acne Erythema ond Pigmentation

    FANG Hui1， CHEN Bin2

    (1.Department of Dermatology，Huangshan People's Hospital，Huangshan 251000， Anhui， China;2.Department of Dermatology， Lujiang County People's Hospital， Anhui Province， Hefei 231500， Anhui， China)

    Abstract：Objective? To explore the clinical effects and safety of Q-switched pulse laser and intensive pulsed light in the treatment of facial acne erythema and pigmentation. Methods? A total of 80 patients with facial acne erythema and pigmentation who were treated at the hospital between March 2018 and March 2020 were divided into Q-switched pulse laser group (33 cases treated with Q-switched pulsed laser) and intensive pulsed light group (47 cases treated with intensive pulsed light) according to the treatment method. Safety of the two treatment methods was evaluated. Clinical effects ......