炎症因子对肥胖大鼠肝脏组织胰岛素信号通路的影响研究
范向宁 刘 柯 朱久育 王 磊 赵清娟 刘 刚 黄艳丽![](/images/paper/1008-6455/202112/28-1-l.jpg)
![](/images/paper/1008-6455/202112/28-2-l.jpg)
![](/images/paper/1008-6455/202112/28-3-l.jpg)
![](/images/paper/1008-6455/202112/28-4-l.jpg)
![](/images/paper/1008-6455/202112/28-5-l.jpg)
[关键词]炎症;肥胖;肝脏;胰岛素;胰岛素抵抗;大鼠
[中图分类号]R365.4? ? [文献标志码]A? ? [文章编号]1008-6455(2021)12-0102-03
Effects of Inflammatory Factors on Insulin Signal Pathway in Liver Tissue
of Obese Rats
FAN Xiang-ning,LIU Ke,ZHU Jiu-yu,WANG Lei,ZHAO Qing-juan,LIU Gang,HUANG Yan-li
(Department of Stomatology,the Third Affiliated Hospital of Xinxiang Medical College,Xinxiang 453000,Henan,China)
Abstract: Objective? The aim of this study was to study the effect of obesity on IR associated with signal pathways in liver. Methods? Ten male SD rats were randomly divided in 2 groups: control group (Con) (fed with standard diet); high-fat diet group (HFD) (fed with high fat diet). The animal model was characterized in terms of body weight (BW) and Lee index. The mRNA levels of tumor necrosis factors ɑ (TNF-ɑ) ......
您现在查看是摘要页,全文长 9958 字符。