裴 培 姬晓伟 韩祥祯 何惠宇

    [关键词]種植体周围炎;单核苷酸多态性;白细胞介素;肿瘤坏死因子-α;金属基质蛋白酶

    [中图分类号]R782.12? ? [文献标志码]A? ? [文章编号]1008-6455(2021)12-0182-04

    Gene Polymorphism as Biomarkers for Diagnosis and Prevention of Peri-implantitis

    PEI Pei1，2， JI Xiao-wei1，2，HAN Xiang-zhen1，2， HE Hui-yu1，2

    (1.Department of Prosthodontics， Stomatological Hospital of the First Affiliated Hospital of Xinjiang Medical University， Urumqi 830054，Xinjiang， China; 2. Institute of Stomatology， Xinjiang Uygur Autonomous Region， Urumqi 830011，Xinjiang，China)

    Abstract： Implant has become the first choice for most patients with missing tooth， although the success rate of implant is over 90%， but there are few patients who is suffering implants failure because of peri-implant inflammation each year. Peri-implantitis is regarded as a multi-factor disease， it cannot be explained by exogenous factors alone， there are a number of studies reported the relationship between SNPs (Single nucleotide polymorphism， SNP) and peri-implantitis. In order to find new molecular diagnostic markers， we discussed the inflammatory factors which have been studied extensively at domestic and overseas (IL ......