基因多态性作为诊断及预防种植体周围炎的生物标记物研究进展
肿瘤坏死因子,白细胞介素
裴 培 姬晓伟 韩祥祯 何惠宇[关键词]種植体周围炎;单核苷酸多态性;白细胞介素;肿瘤坏死因子-α;金属基质蛋白酶
[中图分类号]R782.12? ? [文献标志码]A? ? [文章编号]1008-6455(2021)12-0182-04
Gene Polymorphism as Biomarkers for Diagnosis and Prevention of Peri-implantitis
PEI Pei1,2, JI Xiao-wei1,2,HAN Xiang-zhen1,2, HE Hui-yu1,2
(1.Department of Prosthodontics, Stomatological Hospital of the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054,Xinjiang, China; 2. Institute of Stomatology, Xinjiang Uygur Autonomous Region, Urumqi 830011,Xinjiang,China)
Abstract: Implant has become the first choice for most patients with missing tooth, although the success rate of implant is over 90%, but there are few patients who is suffering implants failure because of peri-implant inflammation each year. Peri-implantitis is regarded as a multi-factor disease, it cannot be explained by exogenous factors alone, there are a number of studies reported the relationship between SNPs (Single nucleotide polymorphism, SNP) and peri-implantitis. In order to find new molecular diagnostic markers, we discussed the inflammatory factors which have been studied extensively at domestic and overseas (IL ......
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