王宁宁 张圣敏 周静 刘超

    [摘要]骨再生的修复中常常需要应用骨组织工程材料，而对于该材料而言，其模拟天然骨的成分和结构与天然骨相容性更高，则更适合于临床应用。为此研究者们研究出了生物陶瓷材料，并以进一步提高其生物活性为目的对其进行了改性。目前，关于锶离子掺杂改性的研究较多，故本文综述了2017年以来掺锶生物陶瓷材料的改性进展，并总结了其在骨科及口腔科中的应用研究。

    [关键词]骨组织工程;生物陶瓷材料;锶;改性;进展

    [中图分类号]R318.08? ? [文献标志码]A? ? [文章编号]1008-6455(2022)02-0166-06

    Research Progress of Strontium-doped Bioceramic Materials for Bone Tissue Engineering

    WANG Ningning1，ZHANG Shengmin1，ZHOU Jing1，LIU Chao2

    (1.Cangzhou Medical College，Cangzhou 061011，Hebei，China;2.Department of Oral and Maxillofacial Surgery，Qilu Hospital of Shandong University，Jinan 250063，Shandong，China)

    Abstract： Bone tissue engineering materials are often used in bone regeneration and repair， and their components and structures that mimic natural bone are more compatible and are more suitable for clinical applications. For this reason， researchers have developed and modified bioceramic materials in order to improve their biological activity. At present， there are many researches on strontium ion doping modification， so this review shows the modification progress of strontium-doped bioceramic materials since 2017 ......