程党党 王飞飞 莫隽颖 殷政 王勤 唐杰

    [摘要]目的：设计一种可用于面部护理的喷雾式富氧水仪，并对其在改善面部寻常痤疮中的临床效果进行探究。方法：筛选30例寻常痤疮患者入组，连续使用富氧水仪进行面部护理，采用自身前后对照方式，于使用前(D0)、使用7 d(D7)、使用14 d(D14)进行仪器测量、临床医生评估和患者自评，并观察改善效果。结果：使用富氧水仪14 d后，患者面部寻常痤疮的面积、体积、红区面积占比以及临床ISGA评分和皮损总数均呈现显著性下降，研究期间无不良反应发生。结论：使用喷雾式富氧水仪进行面部护理，对改善面部寻常痤疮皮损有效。

    [关键词]富氧水；寻常痤疮；痤疮丙酸杆菌；临床研究；面部护理

    [中图分类号]R758.733? ? [文献标志码]A? ? [文章编号]1008-6455(2023)05-0120-04

    Application of Super Oxygen Enriched Water Instrument in the Treatment of Acne

    CHENG Dangdang1，WANG Feifei1，MO Junying2，YIN Zheng2，WANG Qin1，TANG Jie1

    (1.Shanghai Jiyan Bio-pharmaceutical Co.，Ltd.，Shanghai 201702，China; 2.Yunnan Botanee Bio-technology Group Co.，Ltd.，Kunming 650106，Yunnan，China)

    Abstract： Objective? To design a spray instrument of super oxygen enriched water based on micro-nano bubble technology and to evaluate its anti-acne efficacy. Methods 30 patients with a clinical diagnosis of acne were selected and they did facial care with the instrument for a certain time according to the experimental requirements. The facial skin parameters of the subjects before and after the study were compared and analyzed through non-invasive instrumental testing ......