宋姣 陈斌 秦燕 张文娟 鲁楠

    [摘要]本文介绍了皮肤老化的形式及外在皮肤表象，回顾了目前常用抗衰老功效评估方法及各自的优缺点，包括生物化学方法、细胞生物学法、动物试验法和人体试验法，同时着重介绍了皮肤超声、在体荧光光谱法此类新型的评估方法在抗衰老临床评估中的应用，以及不同配方剂型对产品功效性能的影响。

    [关键词]抗衰老；功效评估；体外评估；在体评估；在体荧光光谱法；配方影响

    [中图分类号]R751? ? [文献标志码]A? ? [文章编号]1008-6455(2023)06-0203-03

    Research Progress of Skin Aging Evaluation Methods

    SONG Jiao，CHEN Bin，QIN Yan，ZHANG Wenjuan，LU Nan

    (Shanghai Pechoin Biotechnology Co.Ltd， Shanghai 201499，China)

    Abstract： This paper briefly introduces the form of skin aging and external skin appearance， reviews the common anti-aging efficacy evaluation methods and their advantages and disadvantages， including biochemical method， cell biology method， animal test and human clinical evaluation method， and focuses on the application of new evaluation methods such as skin ultrasound and in vivo fluorescence spectroscopy in the clinical anti-aging evaluation ， and the influence of formulation type on efficacy evaluation.

    Key words： anti-aging; efficacy evaluation; external evaluation; in vivo evaluation; in vivo fluorescence spectrometry; formula influence ......