朱新华 张二佳 付梦瑶

    [摘要]目的：探討超皮秒激光联合透明质酸注射进行面部年轻化治疗的效果。方法：选择2021年1月-2022年6月在笔者医院要求进行面部年轻化治疗的就医者99例，按随机数字表法分为A组(n=33，单纯透明质酸治疗)、B组(n=33，单纯超皮秒激光治疗)、C组(n=33，超皮秒激光联合透明质酸治疗)。评价疗效，对比皮肤生理指标、皮肤屏障功能、不良反应。结果：治疗后，C组总有效率90.91%高于A组(69.70%)及B组(66.67%)(均P<0.05)。C组VISIA皮肤图像分析仪各项指标、经皮水分散失(Trans epidermal water loss，TEWL)、角质层含水量、表皮皮脂含量均较治疗前改善(P<0.05)，且治疗后C组各指标改善均优于A组、B组(P<0.05)。三组不良反应总发生率差异均无统计学意义(P>0.05)。结论：超皮秒激光联合透明质酸注射用于面部年轻化疗效肯定，可改善皮肤生理指标、皮肤屏障功能，且未增加不良反应。

    [关键词]超皮秒激光；透明质酸；面部年轻化；临床效果；美观度

    [中图分类号]R622? ? [文献标志码]A? ? [文章编号]1008-6455(2024)01-0091-04

    Application of Ultra-picosecond Laser Combined with Hyaluronic Acid Injection in Facial Rejuvenation Treatment

    ZHU Xinhua，ZHANG Erjia，FU Mengyao

    (Department of Skin and Plastic Surgery，731 Hospital of China Aerospace Science and Industry Group，Beijing 100074，China)

    Abstract： Objective? To investigate the effect of ultra-picosecond laser combined with hyaluronic acid on the aesthetics of people seeking facial rejuvenation treatment. Methods? A total of 99 people who underwent facial rejuvenation in the author's hospital from January 2021 to June 2022 were selected and grouped into group A (n=33 ......