陈从柏 赵领财 王德运 王浩 朱敏 尹青山

    [摘要]目的：探讨自体纳米脂肪移植治疗慢性难愈性创面的临床疗效。方法：选择2018年9月-2020年5月笔者医院收治的47例慢性难愈性创面患者为研究对象，根据治疗方式的不同分为观察组(24例)和对照组(23例)。两组患者均进行彻底清创，观察组创面行自体纳米脂肪移植治疗，对照组不予纳米脂肪移植，两组均采用“邮票”植皮来闭合创面。比较两组创面愈合及并发症发生情况。结果：术后3周，观察组创面愈合率高于对照组、创面疼痛评分低于对照组(P<0.05)；观察组并发症发生率低于对照组、创面愈合时间短于对照组(P<0.05)。结论：采用自体纳米脂肪移植治疗慢性难愈性创面，可提高创面愈合率，减轻创面疼痛，减少感染等并发症，具有较好的临床效果。

    [关键词]纳米脂肪；脂肪来源干细胞；慢性难愈性创面；脂肪移植；创面愈合

    [中图分类号]R622+.9? ? [文献标志码]A? ? [文章编号]1008-6455(2024)02-0024-04

    Clinical Research on the Treatment of Chronic Refractory Wounds with Autologous Nanofat Transplantation

    CHEN Congbai1，ZHAO Lingcai1，WANG Deyun2，WANG Hao1，ZHU Min1，YIN Qingshan1

    (1.Department of Burn and Plastic Surgery，Tianmen First People's Hospital，Tianmen 431700，Hubei，China; 2.Department of Burns，Wuhan Third Hospital，Wuhan 430074，Hubei，China)

    Abstract： Objective? To investigate the clinical efficacy of autologous nanofat transplantation in the treatment of chronic refractory wounds. Methods? Forty-seven patients with chronic refractory wounds admitted to the author's hospital from September 2018 to May 2020 were selected as the research objects. According to the different treatment methods ......