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电刺激小脑顶核在脑微创术后的应用研究(1)
http://www.100md.com 2011年4月1日 刘旭 黄建军 郑涛 雷琳 匡涛 廖洪民 朱家伟
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     【摘要】目的:探讨电刺激小脑顶核(Eastigial Nucleus Stimulation,FNS)对脑微创术后患者的治疗机理及疗效。方法:将2008年6月-2010年12月在我院收治的高血压脑出血微创术后患者120例,分为治疗组60例,对照组60例;在手术后常规用药基础上均接受现代康复疗法,治疗组加用FNS,测定两组治疗前后患者的卒中量表(NIHSS)及Barthel指数(BI)。结果:治疗前两组NIHSS评分和BI评分比较,无统计学意义(P>0.05),治疗后两组患者的NIHSS评分均降低,BI评分均升高,两组比较有显著统计学意义(P<0.01)。治疗前后NIHSS评分、BI评分比较,治疗组均有显著差异(P<0.01),而对照组NIHSS无统计学意义(P>0.05),BI评分有统计学意义(P<0.05)。两组患者比较,治疗组优于对照组(P<0.05)。结论:电刺激小脑顶核结合现代康复治疗对脑微创术后患者疗效明显,是有效手段之一,值得在临床应用及推广。

    【关键词】电刺激;小脑顶核;脑微创术

    【中图分类号】R743.33【文献标识码】A【文章编号】1008-6455(2011)08-0030-02

    plication Study of Eastigial Nucleus Stimulation in Minimally Invasive Surgery of Brain

    Liu Xu Huang Jianjun Zheng Taoet al.

    【Abstract】Objective: To discuss the mechanism and efficacy of Eastigial Nucleus Stimulation (FNS) for patients with minimally invasive surgery of brain. Methods: 120 cases with minimally invasive surgery of hypertensive cerebral hemorrhage from Jun. 2008 to Dec. 2010 were divided into treatment group and control group, 60 cases in each group. Both groups were given modern rehabilitation therapy on the basis of conventional medicine therapy after operation. Treatment group was added FNS. Two groups’ NIHSS and Barthel index (BI) before and after treatment were measured. Results: Two groups’ NIHSS and BI before treatment had no statistical significance (P>0.05). Both groups’ NIHSS were decreased and BI were increased after treatment, the difference had statistical significance (P<0.01). The difference of treatment group’s NIHSS and BI before and after treatment had obvious difference (P<0.01), while control group’s NIHSS had no statistical significance (P>0.05) and BI had statistical significance (p<0.05). Treatment group’s efficacy was superior to control group (P<0.05). Conclusion: The combination of eastigial nucleus stimulation and modern rehabilitation therapy has obvious effect in minimally invasive surgery of brain. It is worth of spreading in clinic.

    【Key words】Electrical stimulus; Cerebellar fastigial nucleus; Minimally invasive surgery of brain

    高血压脑出血起病急,具有发病率、死亡率、致残率高等特点,近年来发病年龄日渐年轻化,如何降低其病死率及致残率是每一个临床医师关注的焦点 ......

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