热毒宁注射液辅治传染性单核细胞增多症的治疗体会
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【摘要】目的: 辅助治疗传染性单核细胞增多症的疗效研究。方法:将64例传染性单核细胞增多症(IM)患儿随机分为治疗组32例和对照组各32例，两组均予更昔洛韦治疗，剂量10mg/kg/d分两次，加入5%葡萄糖注射液静脉点滴；青霉素抗感染治疗,维生素C及对症支持等治疗，治疗组在此基础上加用热毒宁静滴0.5ml/(kg·d)+生理盐水100～200ml静滴，疗程均为7～14 d。观察两组总有效率和临床症状改善时间。结果治疗组在热程、咽峡炎改善，淋巴结开始缩小，肝脾明显缩小，异型淋巴细胞恢复至<10%的时间均较对照组明显缩短(P<0.01),认为热毒宁辅助治疗传染性单核细胞增多症，对改善患儿的临床症状，缩短病程等具有一定的辅助作用。
【关键词】传染性单核细胞增多症；儿童；更昔洛韦；热毒宁
【Abstract】 OBJECTIVE: To evaluate the clinical efficacy of Reduning injection for the treatment of children's infectious mononucleosis (CIM) METHODS: 64 CIM patients were assigned into the treated group and the control group(32 cases for each group), patients in the control group were treated with intravenous dripping of ganciclovir 10 mg/kg per day, and those in the treated group were administered with Reduning injection in addition, for a treatment course of 7～14 days. RESULTS: The total effective rate was 95.65% in the treated group and 84.21% in the control group, showing significant difference between groups..Conclusion Using Reduning injection can effectively improve the clinical symptoms and shows a certain effect on children's infectious mononucleosis.
【Key words】 infectious mononucleosis syndrome; children; ganciclovir; Reduning
【中图分类号】R272.1【文献标识码】B【文章编号】1008-6455(2011)08-0464-01
传染性单核细胞增多症是一种以EB病毒感染引起的单核一巨噬细胞系统急性传染病。以不规则发热、淋巴结肿大、咽痛、肝脾肿大、皮疹及传染性单核细胞增多为特点。本病过程虽属良性，并具有自限性，但其病程不一，症状复杂多变，往往因免疫异常而致全身多器官受累，在儿童中常见，临床表现多样，病情轻重不一，可有多种并发症。目前临床上治疗该病的药物较少，疗效尚不满意。回顾分析我院64例传染性单核细胞增多症患儿的临床资料。我院对传染性单核细胞增多症在静脉滴注更昔洛韦的基础上加用热毒宁注射液，疗效较好，现报道如下：
1 资料与方法
1.1 一般资料:我院于2007年1月至2009年12月收治传染性单核细胞增多症患儿64例 ......
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