【摘要】复方丹参为临床常用药，有抗心肌缺血，扩冠状动脉，抗心律失常等作用；近期姬洪全等发现复方丹参可以促进家兔骨折中期骨愈合，通过免疫组化显示，在骨折愈合的中期，复方丹参可以促进TGF-β1的表达，提示其可能是通过增加TGF-β1的表达而促进家兔骨折中期骨愈合；种植体一骨界面骨整合的获得是种植体成功的关键，对于骨结合的过程有多种因子参与，其中TGF-β1发挥着重要的作用；通过家兔实验，设对照组，进行不同层次观察，证实复方丹参是否对植体一骨界面骨整合有影响。

    【关键词】复方丹参;种植体;骨整合

    【中图分类号】R782.12 【文献标识码】A 【文章编号】1008-6455(2011)12-0576-02

    【Abstract】Compound Danshen is commonly used in clinical medicine, have anti-myocardial ischemia, coronary artery expansion, anti-arrhythmia effect.And recently Danshen can promote the healing of rabbit bone fracture medium discovered by Ji Hong quan. immunohistochemistry showed that in Medium-term fracture healing term, Compound Danshen can promote the expression of TGF-β1, suggesting that it may promote medium-term bone fracture healing in rabbits by increasing expression of TGF-β1 . Obtaining osseointegration implant-bone interface is key to the success for the combination of bone and there are many factors involving in the process, in which TGF-β1 play an important role. By the control group of rabbit,and the different levels of observation of rabbit, to confirm Compound Danshen affect osseointegration implant-bone interface. ......