【摘要】兰索拉唑是新型质子泵抑制剂，它是奥美拉唑开发后的第二个新型质子泵抑制剂，对基础胃酸分泌和由组胺、五肽胃泌素、二丁基环腺酸、胆碱及食物等引起的胃酸形成与分泌有强力持久的抑制作用，同时对胃肠黏膜有保护作用。为了开发研究此产品,对其合成工艺进行了研究,同时对文献工艺进行了改进,提高了收率,降低了成本,使其更适合工业化的要求.

    关键词：兰索拉唑 奥美拉唑

    Lansoprazolesynthesis craft research

    [ Abstract ] Lansoprazole is the new proton pumps the inhibitor,After it is Om eprazol the development second new proton to pump the inhibitor, To the foundation gastric juice secretion and by the histamine, five peptides stomachs secretes the element, two butyl links gland acid, the choline and food and so on the gastric juice which causes forms with the secretion has the force lasting inhibitory action, Meanwhile has the protective function to the stomach and intestines mucous membrane. In order to develop studies this product,Has conducted the research to its synthesis craft,Meanwhile has made the improvement to the literature craft,Enhanced receiving rate,Reduced the cost, Causes it to suit the industrialization the request.

    [ Key word ] Lansoprazole Om eprazol

    兰索拉唑是目前抗溃疡用药市场的第二大产品 ......