[摘 要] 对莫西沙星和加替沙星治疗女性尿路感染进行成本-效果分析。方法：选自就诊的女性尿路感染患者120例，随机分成两组：莫西沙星组和加替沙星组，运用药物经济学方法对两组进行最小成本-效果分析比较。结果：莫西沙星组和加替沙星组有效率分别为98.34%和96.67%，细菌清除率分别为95.5%和93.2%，不良反应发生率分别为8.33%和10.00%，差异均无显著性(P>0.05)，但成本-效果比分别为211.05和67.49，差异有显著性(P<0.05)。结论：加替沙星比莫西沙星更具成本-效果优势。

    [关键词] 莫西沙星；加替沙星；女性尿路感染；药物经济学；成本-效果

    [Abstract] Objective:To analyze the cost-effectiveness of moxifloxacin and Gatifloxacin in treatment of women's urinary tract infection.Methods:120cases with women's urinary tract infection were randomly divided into 2 groups,in which they were treated with moxifloxacin and Gatifloxacin respectively.The cost-effectiveness in two groups wasanalyzed and compared with each other by pharmacoecono-mical methods.Results:There was no significant difference in therapeutic effect between two groups(P>0.05),such as effective rates of 98.34% and 96.67%,bacterial clearance rates of 95.5% and 93.2% and undesired event rates of 8.33% and 10.00% in moxifloxacin group and gatifloxacin group However,there was significant difference in cost-effectiveness ratio between two group ,211.05 and 67.49 respectively in moxifloxacin group and gatifloxacin group(P<0.05).Conclusion:Gatifloxacin has cost-effective advantage over moxifloxacin in the treatment of urinary tract infection. ......