减毒增效升白汤联合化疗对恶性肿瘤患者免疫学指标的影响(1)
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收稿日期:2009-11-28
基金项目:河北省卫生厅科技攻关计划项目(05178)
作者简介:田翠丽(1975-),女,主治医师,硕士研究生,主要从事中西医结合内科临床工作。
摘 要:目的: 观察减毒增效升白汤联合化疗对恶性肿瘤患者免疫学指标的影响。方法:将200例恶性肿瘤化疗的患者随机分为治疗组和对照组各100例,治疗组服用减毒增效升白汤,1剂/日,水煎服;对照组服用利血生200mg、鲨肝醇100mg,3次/日,口服。两组疗程均4周。试验采用单盲法。观察两组治疗前后免疫学指标变化。结果:治疗后免疫学指标治疗组明显优于对照组,两组比较有显著性差异(P<0.05～0.01)。治疗组治疗后各项指标明显优于治疗前,有显著性差异(P<0.05～0.01)。对照组治疗后只有NK指标优于治疗前,有显著性差异(P<0.01)。结论:减毒增效升白汤可改善免疫学指标,提高机体免疫力,达到减毒增效的作用。
关键词:恶性肿瘤;化学疗法;减毒增效升白汤;免疫学
中图分类号:R285.5 文献标识码:B 文章编号:1673-7717(2010)04-0848-02
Clinical Observation of Chemotherapeutics with Jiandu Zengxiao Shengbai
Decoction on M alignant Tumor
TIAN Cuili,ZHAO Boya, TIAN Cuixia,ZHAO Jubin,WANG Lingfen,BI Hongguan
(Department of TCM,Hebei provincial Geriatric Hospital,Shijiazhuang 050011,Hebei,China)
Abstract:Objective:To sdudy the effect on the immune system of m alignant tumor by chemotherapeutics with Jiandu Zengxiao Shengbai decoction.Methods:200 cases of m alignant tumor were randomly divided into two groups 100 for each.The treatment group was treated by Jiandu Zengxiao Shengbai,dose a day,water be fried.The control group were treated by Leucogen tablet (20mg) and Batilol tablet (100mg),thrice a day,take orally.The therapeutic course was four weeks in both groups.The changes in immune indexes of patients were observed before and after treatment by single blind method.Results: The changes of immune indexes after treatment in treatment group were more obviously better than those in control group (P<0.05 or P<0.01).All indexes were significantly improved after treatment in treatment group than before (P<0.05 or P<0.01).The control group after the treatment only have Natural Killer better than before,have already shown difference (P<0.01). Conclusion: Jiandu Zengxiao Shengbai decoction was more effective on the treatment of m alignant tumor, strengthened the machine body immunity dint, attained to the effect of reducing poison and increasing function.
Key words:m alignant tumor;chemotherapy;Jiandu Zengxiao Shengbai decoction;immunology
化疗是恶性肿瘤最主要的治疗手段,疗效确切,可以使瘤体缩小或消失,但副反应较重,最常见的是骨髓抑制,造成白细胞减少,患者常出现神疲乏力、失眠健忘、腹胀食少及疼痛等反应,严重者不得不延缓或停止治疗。本院自2004年10月-2008年9月用减毒增效升白汤联合化疗治疗恶性肿瘤取得满意疗效,现报道如下 ......
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