战治家 李梓宁

    【摘要】? 目的? 觀察分析抗菌药联合粒细胞集落刺激因子(granulocyte colony stimulating factor，G-CSF)治疗妇科患者恶性肿瘤切除术后淋巴囊肿感染的临床效果。方法? 选择2020年3月- 2021年3月接受不同方案治疗的妇科恶性肿瘤切除术后并发淋巴囊肿感染的患者40例作为研究对象，根据组间年龄、肿瘤类型等基本资料均衡可比的原则分为对照组(20例)和观察组(20例)，对照组采用抗菌药物治疗，观察组采用抗菌药联合G-CSF治疗，对比两组疗效。结果? 观察组治疗有效率显著高于对照组，差异有统计学意义(P<0.05);观察组治疗6d后中性粒细胞水平(absolute neutrophil count，ANC)均低于对照组，差异有统计学意义(P<0.05);观察组发热时间、ANC>1.5×109/L时间显著短于对照组，差异有统计学意义(P<0.05);观察组复发率低于对照组，差异有统计学意义(P<0.05)。结论? 针对恶性肿瘤术后化疗患者发生淋巴囊肿感染，在抗菌药物基础上联合G-CSF治疗有效提高临床疗效，快速退热，降低中性粒细胞水平，缩短患者病程，并有效控制复发率。

    【关键词】? 妇科恶性肿瘤;切除手术;淋巴囊肿感染;抗菌药物;粒细胞集落刺激因子

    中图分类号? R737.3? ? 文献标识码? A? ? 文章编号? 1671-0223(2022)15--03

    【Abstract】? Objective? To observe and analyze the clinical effect of antibiotics combined with granulocyte colony stimulating factor (G-CSF) in the treatment of lymphatic cyst infection after malignant tumor resection in gynecological patients. Methods? A total of 40 patients with lymphatic cyst infection after gynecological malignant tumor resection treated with different schemes from March 2020 to March 2021 were selected as the research object. According to the principle of balanced and comparable basic data such as age and tumor type ......