多发伤患者血清肌酸激酶的动态变化(3)
总之，血清CK浓度与损伤严重程度、继发的全身炎症反应、脏器功能障碍等都有紧密联系。本研究提示血清CK浓度的动态变化能反映严重多发伤患者病情严重程度和发展趋势，帮助判断预后，可作为病情监测的一个有效指标。
参考文献
[1]王正国,创伤学——基础与临床[M].武汉：湖北科学技术出版社，2007:423.
[2] Sahjian M, Frakes M. Crush injuries: pathophysiology and current treatment[J]. Nurse Pract, 2007,32(9):13-18.
[3] James T. Management of patients with acute crush injuries of the extremities[J]. Int Anesthesiol Clin, 2007,45(3):19-29.
[4] Meyer B,Unger A,Nikfardjam M, et al.Critical illness polyneuropathy：incidence and risk factors [J].Critical Care，2006，10 Suppl 1：S461.
[5] Jose GM,Rosario AV,Jose Luis GG,et al.Effect of critical illness polyneuropathy on the withdrawal from mechanical ventilation and the length of stay in septic patients[J].Critl Care Med,2005,33(2):349-354.
[6] 费军,余洪俊,梁华平，等.严重多发伤患者血清降钙素原水平变化与脏器功能不全的相关性[J].中华急诊医学杂志,2007,16(6):572-575.
[7] 李永涛,黄友敏,周永勤.急性脑损伤时内脂素和超敏C-反应蛋白的变化[J].中华急诊医学杂志,2010,19(11):1205-1208.
[8] Hong R.Does the simple triage and rapid treatment method appropriately triage patients based on trauma injury severity score? [J].Am J Disaster Med, 2008,3(5):265-271.
[9] 徐善祥,张茂,干建新，等.多发伤患者血清肌红蛋白的动态变化及临床意义[J].中华创伤杂志,2011,27(1):12-16.
[10]Shlipak MG.Rate of kidney function decline in older adults: a comparison using creatinine and cystatin C[J]. Am J Nephrol, 2009,30(3):171-178.
[11] Dong GT,Wang XJ, Wang MX. The relationship between apolipoprotein AⅠ, C-reactive protein, albumin and the prognosis of systemic inflammatory response syndrome[J]. Chin J merg Medicine, 2007,16(4):418-420.
[12] Vanholder R,Sever MS,Erek E, et al. Acute renal failure related to the crush syndrome: towards an era of seismo-nephrology[J]. Nephrol Dial Transplant, 2000,15(10):1517-1521.
[13] Brown CV, Rhee P, Chan L, et al. Preventing renal failure in patients with rhabdomyolysis: do bicarbonate and mannitol make a difference？[J].J Trauma,2004,56(6):1191-1196.
(收稿日期：2012-01-07)
(本文编辑：沈惠云)
DOI：10.3760/cma.j.issn.1671-0282.2012.08.024
作者单位：310009 杭州,浙江大学急诊医学研究所 浙江大学医学院附属第二医院急诊医学科
通信作者：张茂, Email:zmhz@hotmail.com
中华急诊医学杂志2012年8月第21卷第8期Chin J Emerg Med,August 2012,Vol.21,No.8
P898-901, 百拇医药(徐善祥 张茂 干建新)
参考文献
[1]王正国,创伤学——基础与临床[M].武汉：湖北科学技术出版社，2007:423.
[2] Sahjian M, Frakes M. Crush injuries: pathophysiology and current treatment[J]. Nurse Pract, 2007,32(9):13-18.
[3] James T. Management of patients with acute crush injuries of the extremities[J]. Int Anesthesiol Clin, 2007,45(3):19-29.
[4] Meyer B,Unger A,Nikfardjam M, et al.Critical illness polyneuropathy：incidence and risk factors [J].Critical Care，2006，10 Suppl 1：S461.
[5] Jose GM,Rosario AV,Jose Luis GG,et al.Effect of critical illness polyneuropathy on the withdrawal from mechanical ventilation and the length of stay in septic patients[J].Critl Care Med,2005,33(2):349-354.
[6] 费军,余洪俊,梁华平，等.严重多发伤患者血清降钙素原水平变化与脏器功能不全的相关性[J].中华急诊医学杂志,2007,16(6):572-575.
[7] 李永涛,黄友敏,周永勤.急性脑损伤时内脂素和超敏C-反应蛋白的变化[J].中华急诊医学杂志,2010,19(11):1205-1208.
[8] Hong R.Does the simple triage and rapid treatment method appropriately triage patients based on trauma injury severity score? [J].Am J Disaster Med, 2008,3(5):265-271.
[9] 徐善祥,张茂,干建新，等.多发伤患者血清肌红蛋白的动态变化及临床意义[J].中华创伤杂志,2011,27(1):12-16.
[10]Shlipak MG.Rate of kidney function decline in older adults: a comparison using creatinine and cystatin C[J]. Am J Nephrol, 2009,30(3):171-178.
[11] Dong GT,Wang XJ, Wang MX. The relationship between apolipoprotein AⅠ, C-reactive protein, albumin and the prognosis of systemic inflammatory response syndrome[J]. Chin J merg Medicine, 2007,16(4):418-420.
[12] Vanholder R,Sever MS,Erek E, et al. Acute renal failure related to the crush syndrome: towards an era of seismo-nephrology[J]. Nephrol Dial Transplant, 2000,15(10):1517-1521.
[13] Brown CV, Rhee P, Chan L, et al. Preventing renal failure in patients with rhabdomyolysis: do bicarbonate and mannitol make a difference？[J].J Trauma,2004,56(6):1191-1196.
(收稿日期：2012-01-07)
(本文编辑：沈惠云)
DOI：10.3760/cma.j.issn.1671-0282.2012.08.024
作者单位：310009 杭州,浙江大学急诊医学研究所 浙江大学医学院附属第二医院急诊医学科
通信作者：张茂, Email:zmhz@hotmail.com
中华急诊医学杂志2012年8月第21卷第8期Chin J Emerg Med,August 2012,Vol.21,No.8
P898-901, 百拇医药(徐善祥 张茂 干建新)