脓毒症中NKT细胞的激活机制及其意义(5)
[26] Riedemann NC,Guo RF,Ward PA.Novel strategies for the treatment of sepsis[J]. Nat Med,2003,9(5):517-524.
[27]Rhee RJ, Carlton S, Lomas JL, et al. Inhibition of CD1d activation suppresses septic mortality: a role for NK-T cells in septic immune dysfunction[J]. J Surg Res,2003, 115(1):74-81.
[28] Vinay DS, Choi BK, Bae JS, et al.CD137-deficient mice have reduced NK/NKT cell numbers and function, are resistant to lipopolysaccharide-induced shock syndromes, and have lower IL-4 responses[J] J Immunol,2004,173(6):4218-4229.
[29] Etogo AO,Nunez J,Lin CY,et al. NK but not CD1-restricted NKT cells facilitate systemic inflammation during polymicrobial intra-abdominal sepsis [J]. J Immunol,2008,180(9):6334-6345.
[30] Carnaud C, Lee D, Donnars O, et al. Cutting edge: cross-talk between cells of the innate immune system: NKT cells rapidly activate NK cells[J]. J Immunol,1999, 163(9):4647-4650.
(收稿日期:2012-09-21)
(本文编辑:郑辛甜)
DOI:10.3760/cma.j.issn.1671-0282.2013.03.025
基金项目:国家科技支撑计划儿科应急救治相关技术的研究与推广应用项目(2012BAI04B00)
作者单位:410007 长沙,南华大学儿科学院(湖南省儿童医院)(武周游);湖南省儿童医院急救中心(祝益民)
通信作者:祝益民,Email:cszhuyimin@163.com
中华急诊医学杂志2013年3月第22卷第3期Chin J Emerg Med,March 2013,Vol.22,No.3
P321-P324
, http://www.100md.com(武周游 祝益民)
[27]Rhee RJ, Carlton S, Lomas JL, et al. Inhibition of CD1d activation suppresses septic mortality: a role for NK-T cells in septic immune dysfunction[J]. J Surg Res,2003, 115(1):74-81.
[28] Vinay DS, Choi BK, Bae JS, et al.CD137-deficient mice have reduced NK/NKT cell numbers and function, are resistant to lipopolysaccharide-induced shock syndromes, and have lower IL-4 responses[J] J Immunol,2004,173(6):4218-4229.
[29] Etogo AO,Nunez J,Lin CY,et al. NK but not CD1-restricted NKT cells facilitate systemic inflammation during polymicrobial intra-abdominal sepsis [J]. J Immunol,2008,180(9):6334-6345.
[30] Carnaud C, Lee D, Donnars O, et al. Cutting edge: cross-talk between cells of the innate immune system: NKT cells rapidly activate NK cells[J]. J Immunol,1999, 163(9):4647-4650.
(收稿日期:2012-09-21)
(本文编辑:郑辛甜)
DOI:10.3760/cma.j.issn.1671-0282.2013.03.025
基金项目:国家科技支撑计划儿科应急救治相关技术的研究与推广应用项目(2012BAI04B00)
作者单位:410007 长沙,南华大学儿科学院(湖南省儿童医院)(武周游);湖南省儿童医院急救中心(祝益民)
通信作者:祝益民,Email:cszhuyimin@163.com
中华急诊医学杂志2013年3月第22卷第3期Chin J Emerg Med,March 2013,Vol.22,No.3
P321-P324
, http://www.100md.com(武周游 祝益民)