Conclusions EPO may increase membrane potential levels of chondriosome and decrease the apoptosis rates of myocardial cell in rats after sepsis， and it may reduced the production of inflammatory factors to protect the myocardial cell by down-regulating NF-κB p65. Both increased membrane potential level of chonriosome and decreased inflammatory factor may implicate in myocardium protection thereby improving cardiac function after sepsis.

    【Key words】Sepsis； Myocardial injury； Apoptosis； Chondriosome membrane potential； Nuclear factor κB p65； Erythropoietin； Inflammatory cytokines； Rat

    严重脓毒症时心肌抑制发生率达80% ......