双重抗血小板治疗并发上消化道出血的风险及治疗(3)
[5]Lai K C,Lam S K,Chu K M,et al.Lansoprazole for the prevention of recurrences of ulcer complications from long-term lowdose aspirin use[J].N Engl J Med,2002,346(26):2033-2038.
[6]CAPRIE Investigators.A randomised,blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE).CAPRIE Steering Committee[J].Lancet,1996,348(9038):1329-1339.
[7]Eikelboom J W,Hirsh J.Bleeding and management of bleeding[J].Eur Heart J,2006,8(Suppl G):G38-45.
, 百拇医药
[8]Ng F H,Wong S Y,Chang C M,et al.High incidence of clopidogrel-associated gastrointestinal bleeding in patients with previous peptic ulcer disease[J].Aliment Pharmacol Ther,2003,18(4):443-449.
[9]Yusuf S,Zhao F,Mehta S R,et al.Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation[J].N Engl J Med,2001,345:494-502.
[10]Joseph A D,Lucie O,James M B,et al.Drug-drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding[J].CMAJ,2007,177(4):347-351.
, 百拇医药
[11]CURE Trial Investigators.Effects of aspirin dose when used alone or in combination with clopidogrel in patients with acute coronary syndromes:observations from the Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) study[J].Circulation,2003,108(14):1682-1687.
[12]CHARISMA Investigators.Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events[J].N Engl J Med,2006,354(16):1706-1717.
, 百拇医药
[13]Steven V M,Frederick F,Roxana M,et al.Impact of major bleeding on 30-day mortality and clinical outcomes in patients with acute coronary syndromes[J].J Am Coll Cardiol,2007,49:1362-1368.
[14]Marcus W S,Gerald Y,Max K B,et al.Predictive and protective factors associated with upper gastrointestinal bleeding after percutaneous coronary Intervention: a case-control study[J].Am J Gastroenterol,2007,102:2411-2416.
[15]Abbas A E,Brodie B,Dixon S,et al.Incidence and prognostic impact of gastrointestinal bleeding after percutaneous coronary intervention for acute myocardial infarction[J].Am J Cardiol,2005,96:173-176.
, http://www.100md.com
[16]Twomley K M,Rao S V,Becker R C.Proinflammatory,immunomodulating,and prothrombotic properties of anemia and red blood cell transfusions[J].J Thromb Thrombolysis,2006,21(2):167-174.
[17]Joseph J.Combining aspirin with antithrombotic agents[J].BMJ,2006,333:712-713.
[18]Ng F H,Wong S Y,Lam K F,et al.Gastrointestinal bleeding in patients receiving a combination of aspirin,clopidogrel,and enoxaparin in acute coronary syndrome[J].Am J Gastroenterol,2008,103(4):865-871.
, 百拇医药
[19]Barada K,Karrowni W,Abdallah M,et al.Upper gastrointestinal bleeding in patients with acute coronary syndromes:clinical predictors and prophylactic role of proton pump inhibitors[J].J Clin Gastroenterol,2008,42(4):368-372.
[20]Derry S,Lok Y K.Risk of gastrointestinal hemorrhage with long term use of aspirin: meta-analysis[J].BMJ,2000,321:1183-1187.
[21]Hermosillo A J,Spinler S A.Aspirin,clopidogrel,and warfarin:is the combination appropriate and effective or inappropriate and too dangerous?[J].Ann Pharmacother,2008,42(6):790-805., 百拇医药(朱建祥 范国峰)
[6]CAPRIE Investigators.A randomised,blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE).CAPRIE Steering Committee[J].Lancet,1996,348(9038):1329-1339.
[7]Eikelboom J W,Hirsh J.Bleeding and management of bleeding[J].Eur Heart J,2006,8(Suppl G):G38-45.
, 百拇医药
[8]Ng F H,Wong S Y,Chang C M,et al.High incidence of clopidogrel-associated gastrointestinal bleeding in patients with previous peptic ulcer disease[J].Aliment Pharmacol Ther,2003,18(4):443-449.
[9]Yusuf S,Zhao F,Mehta S R,et al.Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation[J].N Engl J Med,2001,345:494-502.
[10]Joseph A D,Lucie O,James M B,et al.Drug-drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding[J].CMAJ,2007,177(4):347-351.
, 百拇医药
[11]CURE Trial Investigators.Effects of aspirin dose when used alone or in combination with clopidogrel in patients with acute coronary syndromes:observations from the Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) study[J].Circulation,2003,108(14):1682-1687.
[12]CHARISMA Investigators.Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events[J].N Engl J Med,2006,354(16):1706-1717.
, 百拇医药
[13]Steven V M,Frederick F,Roxana M,et al.Impact of major bleeding on 30-day mortality and clinical outcomes in patients with acute coronary syndromes[J].J Am Coll Cardiol,2007,49:1362-1368.
[14]Marcus W S,Gerald Y,Max K B,et al.Predictive and protective factors associated with upper gastrointestinal bleeding after percutaneous coronary Intervention: a case-control study[J].Am J Gastroenterol,2007,102:2411-2416.
[15]Abbas A E,Brodie B,Dixon S,et al.Incidence and prognostic impact of gastrointestinal bleeding after percutaneous coronary intervention for acute myocardial infarction[J].Am J Cardiol,2005,96:173-176.
, http://www.100md.com
[16]Twomley K M,Rao S V,Becker R C.Proinflammatory,immunomodulating,and prothrombotic properties of anemia and red blood cell transfusions[J].J Thromb Thrombolysis,2006,21(2):167-174.
[17]Joseph J.Combining aspirin with antithrombotic agents[J].BMJ,2006,333:712-713.
[18]Ng F H,Wong S Y,Lam K F,et al.Gastrointestinal bleeding in patients receiving a combination of aspirin,clopidogrel,and enoxaparin in acute coronary syndrome[J].Am J Gastroenterol,2008,103(4):865-871.
, 百拇医药
[19]Barada K,Karrowni W,Abdallah M,et al.Upper gastrointestinal bleeding in patients with acute coronary syndromes:clinical predictors and prophylactic role of proton pump inhibitors[J].J Clin Gastroenterol,2008,42(4):368-372.
[20]Derry S,Lok Y K.Risk of gastrointestinal hemorrhage with long term use of aspirin: meta-analysis[J].BMJ,2000,321:1183-1187.
[21]Hermosillo A J,Spinler S A.Aspirin,clopidogrel,and warfarin:is the combination appropriate and effective or inappropriate and too dangerous?[J].Ann Pharmacother,2008,42(6):790-805., 百拇医药(朱建祥 范国峰)