全身给予LPD液预处理对油酸诱导的幼猪急性肺损伤模型血气和血流动力学的影响(2)
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LPD并不能阻止ALI的发生,而是缓解了病情。OA给予的剂量、方法、时间等都会对ALI的程度造成影响。本实验采用的动物数量较少,观察时间仅延续到ALI发生后4 h,这不能完全反映出ALI的进程。所以还需要进一步的实验来探讨LPD对ALI的影响。
总之,实验数据显示,自外周静脉给予LPD进行预处理后,可以改善油酸诱导的幼猪ALI模型的低氧血症,降低肺动脉高压。
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