芪苈强心胶囊治疗慢性心力衰竭临床疗效观察
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摘要：目的 观察芪苈强心胶囊治疗慢性心力衰竭的临床疗效。方法 将80例慢性心力衰竭患者随机分为两组。对照组40例，予西医常规抗心衰治疗。治疗组40例，在对照组的基础上加服芪苈强心胶囊，每次4粒，每日3次。两组均连续治疗6 个月。结果 治疗组心力衰竭中医证候疗效显效率37.5%，总有效率92.5%，明显优于对照组。治疗组心功能疗效显效率45.0%，总有效率95.0%，明显优于对照组。治疗后两组B型利钠肽(BNP)均较治疗前明显降低，治疗后治疗组BNP较对照组低(P<0.05)。结论 芪苈强心胶囊结合西医常规治疗能改善慢性心力衰竭患者临床症状、心功能，降低BNP含量。
关键词：慢性心力衰竭；芪苈强心胶囊；B型利钠肽
中图分类号：R541.6 R289.5 文献标识码：B 文章编号：1672-1349(2011)07-0769-02
Clinical Observation of Qili Qiangxin Capsule for Treatment of Chronic Heart Failure
Wang Lingjun，Liu Jing，Wang Gongfeng
The First Hospital，Guangzhou University of Traditional Chinese Medicine(Guangzhou510405)
Abstract：Objective To investigate the effect of Qili Qiangxin capsule(QQC)for treatment of chronic heart failure(CHF).Methods Eighty patients with CHF were randomly divided into two groups：Control group(n40) treated by routine western medicine treatment，and treatment group(n40) treated by QQC on the basis of routine treatment for six months.Results The efficiency rate and total clinical effective rate of Traditional Chinese Medicine(TCM)symptom was 37.5% and 92.5% in treatment group，which was was significantly higher than that in control group(P<0.05).The efficiency rate and total clinical effective rate of heart function was 45.0% and 95.0% in treatment group，which was was significantly higher than that in control group(P<0.05).After treatment，the levels of serum B-type natriuretic peptide (BNP) were decreased in control group and treatment group.The levels of serum BNP in treatment group were lower than that in control group.Conclusion QQC with routine western medicine treatment could improve heart failure，symptoms and quality of life in patients with CHF.
Key words：chronic heart failure；Qili Qiangxin capsule；clinical efficiency
芪苈强心胶囊具有益气温阳，活血通络，利水消肿的功效。本研究旨在评价芪苈强心胶囊治疗慢性心力衰竭的疗效。
1 资料与方法
1.1 诊断标准 参照《临床心脏病学》中充血性心力衰竭诊断标准制定[1]。心功能分级标准参照纽约心脏病协会(NYHA)分级标准[2]拟定。 心阳虚证中医辨证标准参照《中药新药临床研究指导原则》(2002年版)制定。纳入标准，符合慢性心力衰竭的诊断标准，NYHA心功能分级Ⅱ级～Ⅳ级，ACC/AHA补充分级C阶段患者，年龄18岁～80岁。
1.2 一般资料 共入选80例，随机分为两组。治疗组40例，男性22例，女性18例；年龄69.11岁±5.33岁；病程7.13年±3.76年 ......
摘要：目的 观察芪苈强心胶囊治疗慢性心力衰竭的临床疗效。方法 将80例慢性心力衰竭患者随机分为两组。对照组40例，予西医常规抗心衰治疗。治疗组40例，在对照组的基础上加服芪苈强心胶囊，每次4粒，每日3次。两组均连续治疗6 个月。结果 治疗组心力衰竭中医证候疗效显效率37.5%，总有效率92.5%，明显优于对照组。治疗组心功能疗效显效率45.0%，总有效率95.0%，明显优于对照组。治疗后两组B型利钠肽(BNP)均较治疗前明显降低，治疗后治疗组BNP较对照组低(P<0.05)。结论 芪苈强心胶囊结合西医常规治疗能改善慢性心力衰竭患者临床症状、心功能，降低BNP含量。
关键词：慢性心力衰竭；芪苈强心胶囊；B型利钠肽
中图分类号：R541.6 R289.5 文献标识码：B 文章编号：1672-1349(2011)07-0769-02
Clinical Observation of Qili Qiangxin Capsule for Treatment of Chronic Heart Failure
Wang Lingjun，Liu Jing，Wang Gongfeng
The First Hospital，Guangzhou University of Traditional Chinese Medicine(Guangzhou510405)
Abstract：Objective To investigate the effect of Qili Qiangxin capsule(QQC)for treatment of chronic heart failure(CHF).Methods Eighty patients with CHF were randomly divided into two groups：Control group(n40) treated by routine western medicine treatment，and treatment group(n40) treated by QQC on the basis of routine treatment for six months.Results The efficiency rate and total clinical effective rate of Traditional Chinese Medicine(TCM)symptom was 37.5% and 92.5% in treatment group，which was was significantly higher than that in control group(P<0.05).The efficiency rate and total clinical effective rate of heart function was 45.0% and 95.0% in treatment group，which was was significantly higher than that in control group(P<0.05).After treatment，the levels of serum B-type natriuretic peptide (BNP) were decreased in control group and treatment group.The levels of serum BNP in treatment group were lower than that in control group.Conclusion QQC with routine western medicine treatment could improve heart failure，symptoms and quality of life in patients with CHF.
Key words：chronic heart failure；Qili Qiangxin capsule；clinical efficiency
芪苈强心胶囊具有益气温阳，活血通络，利水消肿的功效。本研究旨在评价芪苈强心胶囊治疗慢性心力衰竭的疗效。
1 资料与方法
1.1 诊断标准 参照《临床心脏病学》中充血性心力衰竭诊断标准制定[1]。心功能分级标准参照纽约心脏病协会(NYHA)分级标准[2]拟定。 心阳虚证中医辨证标准参照《中药新药临床研究指导原则》(2002年版)制定。纳入标准，符合慢性心力衰竭的诊断标准，NYHA心功能分级Ⅱ级～Ⅳ级，ACC/AHA补充分级C阶段患者，年龄18岁～80岁。
1.2 一般资料 共入选80例，随机分为两组。治疗组40例，男性22例，女性18例；年龄69.11岁±5.33岁；病程7.13年±3.76年 ......
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