拉米呋啶联合肝苏颗粒治疗慢性乙型肝炎疗效观察(1)
中图分类号：R512.6+2文献标识码： A
文章编号： 1672-3783(2008)-6-0013-02
【摘 要】目的 随访拉米呋啶联合肝苏颗粒治疗慢性乙型肝炎(CHB)疗效及治疗后效应。方法选择CHB病例124例，随机分为观察组和对照组。观察组口服拉米呋啶100mg/次，1次/天，肝苏颗粒9g/次，3次/天；对照组单用拉米呋啶，疗程12个月，停药后随访6个月。 结果 疗程结束时两组HBV-DNA阴转率、HbeAg、HBeAb转换率及ALT复常率差异、肝肝纤维化程度均有显著性意义(P<0.05)。停药6月后随访，仍存在显著性意义。结论 拉米呋啶联合肝苏颗粒治疗CHB具有良好改善肝功能和抗HBV作用，且其疗效持久，安全。
【关键词】拉米呋啶 肝苏颗粒 慢性乙型肝炎
Effection for Chronic Hepatitis B with Lam ivudine and Gansu granule
DENG Xiao-Lin
The People’s Hospital of Zi Yang, Si Chuan,641301 China
【Abstract】Objective To observe the effection and the post-effection of the patients with chronic hepatitis B after using Lam ivudine and Gansu granule.Methods 124 cases of chronic hepatitis B were divided into study group and control group. Study group with Lam ivudine 100mg qd, Gansu granule 9g tid; control group with Lam ivudine 100mg qd only, both groups for 12 months, and go on visit after 6 months.Results Study group and control group serum HBV-DNA darkening rate,conversion rate of HBeAg/HbeAb and the comeback of ALT were obviously different with statistical significane (P<0.05). The post-effection after 6 months in study group was still obvious.Conlusion Lam ivudine and Gansu granule can partly resume the hepatic function and anti-HBV in patients with chronic hepatitis B,furthermore the effection was safe and effective. ......
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