短化方案治疗肺结核的毒副反应临床观察
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【中图分类号】R521.05 【文献标识码】A 【文章编号】1672-3783(2011)02-0036-02
【摘要】目的:为探索短化方案在治疗肺结核病人中毒副作用发生的频度、强度。方法:对805例肺结核病人采用全球基金结核控制项目统一短化方案治疗。结果:毒副反应发生率85%,其中胃肠道反应占40.2%;因毒副反应严重而终止治疗占13%。约80%的毒副反应发生在用药2个月内。 结论:认为毒副反应发生与化疗方案中药物组成多、剂量偏大、空腹服药及个体差异等有关。
【关键词】短化;肺结核;毒副反应
Clinical observation of the toxic and adverse reaction of the short-course chemotherapy in treating pulmonary tuberculosis
Lai Guangming
【Abstract】Objective:To study the frequency and intensity of the toxic and adverse reaction of the short-course chemotherapy in treating the tuberculosis patients.Methods:Use the united short-course chemotherapy with the global fund of TB control project for 805 tuberculosis patients .Results:The response rates of the toxic and adverse reaction was 85%, and the response rates of the gastrointestinal was 40 ......
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