【中图分类号】R554.6 【文献标识码】A 【文章编号】1672-3783(2011)07-0018-02

    【摘要】目的 探讨脾切除加门体静脉断流术后发生门静脉系统血栓(PVT)的原因。方法 对117例需施行脾切除加门体静脉断流术的门静脉高压伴脾功能亢进患者展开前瞻性研究，选取性别、年龄、血小板计数(PLT)、凝血酶原时间(PT)、肝功能、门脉压变化及脾脏重量作为观察指标，对术后并发PVT的原因进行比较和多因素Logistic回归分析。结果与结论PVT的发生主要与术后PLT升高、脾脏重量和门脉压下降有关(P<0.05)，与年龄、性别、脾静脉直径、PT和肝功能变化无关(P>0.05)。据此加强术后的早期评估，做到早期预防和治疗，可减少PVT的危害。

    【关键词】高血压，门脉脉；血栓形成；脾脏摘除；断流术

    Analysis of Portal Vein Thrombosis after Splenectomy and Portosystemic Devascularization

    WANG Yuan-xi* ， LI Zhi-wei ，CAI Lie ， ZHENG Yu ，CHEN Jin.* Kanghua Hospital ， Guangdong， Dongguan ， 523080 ， China

    【Abstract】Objective: To explore the reason for portal vein thrombosis(PVT) after splenectomy and portosystemic devascularization.Methods: 117 patients who required portal hypertension operation, were in the prospective study. Observed indicators included age, gender, platelet count(PLT), prothrombin time(PT), liver function, portal pressure changes, splenic vein diameter and spleen weight. And the reason for postoperative PVT was compared and analyzed by multivariate Logistic regression. Result and conclusion: PLT, spleen quality and portal pressure have a close relationship with the development of PST (P<0.05). The age, sex, liver function, PT and splenic vein diameter did not show significant effect on the occurrence of PST (P>0.05). Accordingly, the early postoperative evaluation, prevention and treatment can reduce the risk of PVT. ......