【摘 要】目的：对比分析使用阿托伐他汀与辛伐他汀治疗原发性高脂血症的临床有效性，并分析其药理作用。方法：本次的样本量均选自我院接收并治疗的原发性高脂血症患者中，共78例；根据不同治疗方法分为两组，使用阿托伐他汀治疗的39例为A组，使用辛伐他汀治疗的39例为B组，对比两组治疗后的疗效及药理。结果：治疗后，A组TG、HDL-C、TC、LDL-C水平优于B组，P<0.05；且A组总有效率94.87%，优于B组的76.92%，P<0.05。结论：使用阿托伐他汀治疗原发性高脂血症的临床效果较辛伐他汀治疗的疗效更为显著，且无明显不良反应，值得推广。

    【关键词】阿托伐他汀；辛伐他汀；原发性高脂血症；药理

    Abstract Objective：to compare the clinical efficacy of atorvastatin and simvastatin in the treatment of primary hyperlipidemia and to analyze its pharmacological effects. Methods： 78 cases of primary hyperlipidemia patients received and treated by self-hospital were selected. According to different treatment methods ......