【摘 要】：目的：探讨高龄心力衰竭(HF)患者血浆N-末端脑钠肽(NT—proBNP)与心力衰竭严重程度的关系，评价其对高龄心力衰竭患者的临床意义。方法：年龄≥80岁心力衰竭患者81例，根据纽约心脏病协会(NYHA)心功能分级，其中NYHAⅡ级28例、Ⅲ级35例、Ⅳ级18例，同时选取35例心功能正常老年人作为对照组，分别测定血浆NT—proBNP值及左室射血分数(LVEF)。结果：老年心力衰竭组NT—proBNP数值明显高于对照组，且其数值随心功能分级的升高而增高，与LVEF呈负相关(P〈0.05)。结论：老年心力衰竭患者血NT—proBNP水平与心力衰竭严重程度存在相关性，可客观反映老年心力衰竭患者的心功能状态。

    【关键词】：老年;N-末端脑钠肽;心力衰竭;左室射血分数

    Abstract： Objective： To investigate the relationship between N-terminal pro-brain natriuretic peptide (NT-proBNP) levels in elderly patients with the deterioration of the heart failure severity. Methods All of 81 elderly patiants with heat failure were selected ......